Two New Sesquiterpene Polyol Esters from Celastrus angulatus

被引：7

作者：

Wei, Shao-Peng ^{[1
]}

Wu, Wen-Jun ^{[1
]}

Ji, Zhi-Qin ^{[1
]}

Zhang, Ji-Wen ^{[2
]}

Guo, Yong-Ze ^{[3
]}

Xue, Jian ^{[4
]}

机构：

[1] NW A&F Univ, Inst Pesticides, Yangling 712100, Shaanxi, Peoples R China

[2] NW A&F Univ, Coll Sci, Yangling 712100, Shaanxi, Peoples R China

[3] Tianjin Acad Agr Sci, Cent Lab, Tianjin 300381, Peoples R China

[4] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2010年 / 93卷 / 09期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

P-GLYCOPROTEIN; INSECTICIDAL SESQUITERPENOIDS; MULTIDRUG-RESISTANCE; LEISHMANIA; MODULATORS; ALKALOIDS;

D O I：

10.1002/hlca.200900473

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two novel sesquiterpene polyol esters with a dihydro-beta-agarofuran (=(3R,5aS,9R,9aS)-octahydro-2,2,5a,9-tetramethyl-2H-3,9a-methano-1-benzoxepin) skeleton, (1 alpha,2 alpha,4 beta,8 alpha,9 alpha)-1,2,8,12-tetrakis(acetyloxy)-9-(furoyloxy)-4-hydroxydihydro-beta-agarofuran (1) and (1 alpha,2 alpha,6 beta,8 alpha,9 alpha)-1,2,6,8,12-pentakis(acetyloxy)-9-(benzoyloxy)dihydro-beta-agarofuran (2), and the three known compounds (1 alpha,2 alpha,4 beta,6 beta,8 alpha,9 beta)-1,2,6-tris(acetyloxy)-9-(benzoyloxy)-4-hydroxy-8,12-bis(isobutyryloxy)dihydro-beta-agarofuran (3), (1 alpha,2 alpha,4 beta,6 beta,8 alpha,9 beta)-1,2,6,8-tetrakis(acetyloxy)-9-(furoyloxy)-4-hydroxy-12-isobutyryloxy)dihydro-beta-agarofuran (4), and (1 alpha,2 alpha,4 beta,6 beta,8 alpha,9 beta)-1,2,6-tris(acetyloxy)-9-(benzoyloxy)-4-hydroxy-8-(isobutyryloxy)-12-[(2-methylbutanoyl)oxy]dihydro-beta-agarofuran (5) were isolated from the root bark of Celastrus angulatus. Their chemical structures were elucidated by analyses of their MS and NMR data.

引用

页码：1844 / 1850

页数：7

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