Pentafluorophenylammonium triflate as a suitable and effective metal-free catalyst for the synthesis of quinazoline derivatives via one-pot multicomponent method

被引：8
|
作者：
Khaksar, Samad [1 ]
Gholami, Milad [1 ]
机构：
[1] Islamic Azad Univ, Ayatollah Amoli Branch, Dept Chem, Amol, Iran
来源：
RESEARCH ON CHEMICAL INTERMEDIATES | 2015年 / 41卷 / 06期
关键词：
Organocatalyst; Metal-free; Quinazoline; PFPAT; EFFICIENT SYNTHESIS; KETONES; MILD; 2,3-DIHYDROQUINAZOLIN-4(1H)-ONES; ORGANOCATALYSIS; INHIBITORS; ALDEHYDES; PFPAT;
D O I：
10.1007/s11164-013-1483-7
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and facile synthesis of highly functionalized quinazoline derivatives has been successfully developed by treatment of aldehydes, ammonium acetate, and 2-aminoaryl ketones or isatoic anhydride under reflux conditions in the presence of a pentafluorophenylammonium triflate (PFPAT) organocatalyst. These catalytic condensation reactions represent green chemical processes, while the PFPAT organocatalyst is air-stable, cost-effective, easy to handle, and easily removed from the reaction mixtures.
引用
收藏
页码：3709 / 3718
页数：10
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