IL-27: a new target for GVHD prevention

被引:0
作者
Fowler, Daniel H. [1 ]
Amarnath, Shoba [2 ]
机构
[1] NIH, Bldg 10, Bethesda, MD 20892 USA
[2] Newcastle Univ, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
关键词
T-CELLS; INTERLEUKIN-27; INFLAMMATION;
D O I
10.1182/blood-2016-08-732974
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2003 / 2004
页数:2
相关论文
共 10 条
[1]   A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells [J].
Awasthi, Amit ;
Carrier, Yijun ;
Peron, Jean P. S. ;
Bettelli, Estelle ;
Kamanaka, Masahito ;
Flavell, Richard A. ;
Kuchroo, Vijay K. ;
Oukka, Mohamed ;
Weiner, Howard L. .
NATURE IMMUNOLOGY, 2007, 8 (12) :1380-1389
[2]   Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression [J].
Belle, Ludovic ;
Agle, Kimberle ;
Zhou, Vivian ;
Yin-Yuan, Cheng ;
Komorowski, Richard ;
Eastwood, Daniel ;
Logan, Brent ;
Sun, Jie ;
Ghilardi, Nico ;
Cua, Daniel ;
Williams, Calvin B. ;
Gaignage, Melanie ;
Marillier, Reece ;
van Snick, Jacques ;
Drobyski, William R. .
BLOOD, 2016, 128 (16) :2068-2082
[3]   Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells [J].
Fitzgerald, Denise C. ;
Zhang, Guang-Xian ;
El-Behi, Mohamed ;
Fonseca-Kelly, Zoe ;
Li, Hongmei ;
Yu, Shuo ;
Saris, Christiaan J. M. ;
Gran, Bruno ;
Ciric, Bogoljub ;
Rostami, Abdolmohamad .
NATURE IMMUNOLOGY, 2007, 8 (12) :1372-U6
[4]   Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1 [J].
Hirahara, Kiyoshi ;
Ghoreschi, Kamran ;
Yang, Xiang-Ping ;
Takahashi, Hayato ;
Laurence, Arian ;
Vahedi, Golnaz ;
Sciume, Giuseppe ;
Hall, Aisling O'Hara ;
Dupont, Christopher D. ;
Francisco, Loise M. ;
Chen, Qian ;
Tanaka, Masao ;
Kanno, Yuka ;
Sun, Hong-Wei ;
Sharpe, Arlene H. ;
Hunter, Christopher A. ;
O'Shea, John J. .
IMMUNITY, 2012, 36 (06) :1017-1030
[5]   Donor-type CD4+CD25+ regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation [J].
Hoffmann, P ;
Ermann, J ;
Edinger, M ;
Fathman, CG ;
Strober, S .
JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 196 (03) :389-399
[6]   The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation [J].
Koch, Meghan A. ;
Tucker-Heard, Glady's ;
Perdue, Nikole R. ;
Killebrew, Justin R. ;
Urdahl, Kevin B. ;
Campbell, Daniel J. .
NATURE IMMUNOLOGY, 2009, 10 (06) :595-U57
[7]   IL-27 mediates complete regression of orthotopic primary and metastatic murine neuroblastoma tumors:: Role for CD8+ T cells [J].
Salcedo, R ;
Stauffer, JK ;
Lincoln, E ;
Back, TC ;
Hixon, JA ;
Hahn, C ;
Shafer-Weaver, K ;
Malyguine, A ;
Kastelein, R ;
Wigginton, JM .
JOURNAL OF IMMUNOLOGY, 2004, 173 (12) :7170-7182
[8]   Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease [J].
Yi, Tangsheng ;
Chen, Ying ;
Wang, Lin ;
Du, Gong ;
Huang, Daniel ;
Zhao, Dongchang ;
Johnston, Heather ;
Young, James ;
Todorov, Ivan ;
Umetsu, Dale T. ;
Chen, Lieping ;
Iwakura, Yoichiro ;
Kandeel, Fouad ;
Forman, Stephen ;
Zeng, Defu .
BLOOD, 2009, 114 (14) :3101-3112
[9]   The Immunobiology of Interleukin-27 [J].
Yoshida, Hiroki ;
Hunter, Christopher A. .
ANNUAL REVIEW OF IMMUNOLOGY VOL 33, 2015, 33 :417-443
[10]   Interleukin-27 Inhibits the Growth of Pediatric Acute Myeloid Leukemia in NOD/SCID/Il2rg -/- Mice [J].
Zorzoli, Alessia ;
Di Carlo, Emma ;
Cocco, Claudia ;
Ognio, Emanuela ;
Ribatti, Domenico ;
Ferretti, Elisa ;
Dufour, Carlo ;
Locatelli, Franco ;
Montagna, Daniela ;
Airoldi, Irma .
CLINICAL CANCER RESEARCH, 2012, 18 (06) :1630-1640