Contribution for an African autosomic STR database (AmpF/STR Identifiler and Powerplex 16 System) and a report on genotypic variations

被引:50
作者
Alves, C
Gusmao, L
Damasceno, A
Soares, B
Amorim, A
机构
[1] IPATIMUP, P-4200 Oporto, Portugal
[2] Eduardo Mondlane Univ, Fac Med, Maputo, Mozambique
[3] Univ Porto, Fac Sci, Oporto, Portugal
关键词
STRs population data; AmpF/STR Identifiler Powerplex 16 System Mozambique; nall alleles; triplet allele patterns;
D O I
10.1016/j.forsciint.2003.11.002
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Allele frequencies, together with some parameters of forensic interest, for 17 STRs included in the AmpF/STR Identifiler (CSF1PO, D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPO and VWA) and Powerplex 16 System (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, TH01, TPO and VWA) were estimated from a sample of 135-144 unrelated individuals from Mozambique. No deviations from Hardy-Weinberg equilibrium were observed with the exception of the FGA locus (using the Bonferroni correction for the number of loci analysed, the departure observed at this locus was not significant). Comparative analyses between our Population data and other African databases, namely Promega's African-Americans, AB Applied Biosystems African-Americans and two Other Population samples from Mozambique and Guine Bissau, are presented and discussed. Genotype inconsistencies between both commercial kits (for D16S539 and D8S1179) and other genotypic variations (three-banded allele patterns for TPO) are also reported. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:201 / 205
页数:5
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