Soft-tissue sarcoma in adults: An update on the current state of histiotype-specific management in an era of personalized medicine

被引：416

作者：

Gamboa, Adriana C. ^{[1
]}

Gronchi, Alessandro ^{[2
]}

Cardona, Kenneth ^{[3
]}

机构：

[1] Emory Univ, Sch Med, Dept Surg, Div Surg Oncol, Atlanta, GA 30322 USA

[2] Fdn IRCCS Ist Nazl Tumori, Dept Surg, Milan, Italy

[3] Emory Univ Hosp Midtown, Div Surg Oncol, Winship Canc Inst, 550 Peachtree St NE,Suite 900, Atlanta, GA 30308 USA

来源：

CA-A CANCER JOURNAL FOR CLINICIANS | 2020年 / 70卷 / 03期

关键词：

advanced soft-tissue sarcoma; extremity sarcoma; retroperitoneal sarcoma; soft-tissue sarcoma; DESMOID-TYPE FIBROMATOSIS; RANDOMIZED PHASE-II; METASTATIC UTERINE LEIOMYOSARCOMA; MODULATED RADIATION-THERAPY; ISOLATED LIMB PERFUSION; LONG-TERM SURVIVAL; PROGNOSTIC-FACTORS; RETROPERITONEAL SARCOMA; NEOADJUVANT CHEMOTHERAPY; LOCAL RECURRENCE;

D O I：

10.3322/caac.21605

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Soft-tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies, with over 100 different histologic subtypes occurring predominately in the trunk, extremity, and retroperitoneum. This low incidence is further complicated by their variable presentation, behavior, and long-term outcomes, which emphasize the importance of centralized care in specialized centers with a multidisciplinary team approach. In the last decade, there has been an effort to improve the quality of care for patients with STS based on anatomic site and histology, and multiple ongoing clinical trials are focusing on tailoring therapy to histologic subtype. This report summarizes the latest evidence guiding the histiotype-specific management of extremity/truncal and retroperitoneal STS with regard to surgery, radiation, and chemotherapy.

引用

页码：200 / 229

页数：30

共 271 条

[1] Improved survival for extremity soft tissue sarcoma treated in high-volume facilities [J].

Abarca, Tyler ;

Gao, Yubo ;

Monga, Varun ;

Tanas, Munir R. ;

Milhem, Mohammed M. ;

Miller, Benjamin J. .

JOURNAL OF SURGICAL ONCOLOGY, 2018, 117 (07) :1479-1486

[2] Volume-Outcome Relationships in the Treatment of Renal Tumors [J].

Abouassaly, Robert ;

Finelli, Antonio ;

Tomlinson, George A. ;

Urbach, David R. ;

Alibhai, Shabbir M. H. .

JOURNAL OF UROLOGY, 2012, 187 (06) :1984-1988

[3] Outcomes and Prognostic Factors for a Consecutive Case Series of 115 Patients with Somatic Leiomyosarcoma [J].

Abraham, John A. ;

Weaver, Michael J. ;

Hornick, Jason L. ;

Zurakowski, David ;

Ready, John E. .

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2012, 94A (08) :736-744

[4] Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group [J].

Ahlen, Jan ;

Ahuja, Nita ;

Antbacka, Robert ;

Bagaria, Sanjay ;

Blay, Jean-Yves ;

Bonvalot, Sylvie ;

Callegaro, Dario ;

Canter, Robert J. ;

Cardona, Kenneth ;

Casali, Paolo G. ;

Colombo, Chiara ;

Dei Tos, Angelo P. ;

De Paoli, Antonino ;

Desai, Anant ;

Dickson, Brendan C. ;

Eilber, Fritz C. ;

Fiore, Marco ;

Fletcher, Cristopher D. ;

Ford, Samuel J. ;

Gelderblom, Hans J. ;

Gonzalez, Ricardo ;

Grignani, Giovanni ;

Grignol, Valerie ;

Gronchi, Alessandro ;

Haas, Rick L. ;

Hayes, Andrew J. ;

Hartmann, Wolfgang ;

Henzler, Thomas ;

Hohenberger, Peter ;

Italiano, Antoine ;

Jakob, Jens ;

Jones, Robin L. ;

Judson, Ian ;

Kane, John M., III ;

Lahat, Guy ;

MacNeill, Andrea J. ;

Maestro, Roberta ;

Messiou, Christina ;

Meeus, Pierre ;

Miceli, Rosalba ;

Mullen, John T. ;

Nessim, Carolyn ;

Pennacchioli, Elisabetta ;

Pillarisetty, Vinu G. ;

Pollock, Raphael E. ;

Quagliuolo, Vittorio ;

Radaelli, Stefano ;

Raut, Chandrajit P. ;

Rutkowski, Piotr ;

Sandrucci, Sergio .

ANNALS OF SURGICAL ONCOLOGY, 2016, 23 (11) :3531-3540

[5] External Beam Radiation Therapy for Resectable Soft Tissue Sarcoma: A Systematic Review and Meta-Analysis [J].

Albertsmeier, Markus ;

Rauch, Alexandra ;

Roeder, Falk ;

Hasenhuetl, Sandro ;

Pratschke, Sebastian ;

Kirschneck, Michaela ;

Gronchi, Alessandro ;

Jebsen, Nina L. ;

Cassier, Philippe A. ;

Sargos, Paul ;

Belka, Claus ;

Lindner, Lars H. ;

Werner, Jens ;

Angele, Martin K. .

ANNALS OF SURGICAL ONCOLOGY, 2018, 25 (03) :754-767

[6] Impact of intensity-modulated radiation therapy on local control in primary soft-tissue sarcoma of the extremity [J].

Alektiar, Kaled M. ;

Brennan, Murray F. ;

Healey, John H. ;

Singer, Samuel .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (20) :3440-3444

[7] Adjuvant radiotherapy for margin-positive high-grade soft tissue sarcoma of the extremity [J].

Alektiar, KM ;

Velasco, J ;

Zelefsky, MJ ;

Woodruff, JM ;

Lewis, JJ ;

Brennan, MF .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2000, 48 (04) :1051-1058

[8] The management of desmoid tumours: A joint global consensus-based guideline approach for adult and paediatric patients [J].

Alman, Ben ;

Attia, Steven ;

Baumgarten, Christina ;

Benson, Charlotte ;

Blay, Jean-Yves ;

Bonvalot, Sylvie ;

Breuing, Jessica ;

Cardona, Ken ;

Casali, Paolo G. ;

van Coevorden, Frits ;

Colombo, Chiara ;

Tos, Angelo P. Dei ;

Dileo, Palma ;

Ferrari, Andrea ;

Fiore, Marco ;

Frezza, Anna M. ;

Garcia, Jesica ;

Gladdy, Rebecca ;

Gounder, Mrinal ;

Gronchi, Alessandro ;

Haas, Rick ;

Hackett, Sam ;

Haller, Florian ;

Hohenberger, Peter ;

Husson, Olga ;

Jones, Robin L. ;

Judson, Ian ;

Kasper, Bernd ;

Kawai, Akira ;

Kogosov, Vlada ;

Lazar, Alex J. ;

Maki, Robert ;

Mathes, Tim ;

Messiou, Christina ;

Navid, Fariba ;

Nishida, Yoshihiro ;

Palassini, Elena ;

Penel, Nicolas ;

Pollock, Robert ;

Pieper, Dawid ;

Portnoy, Marlene ;

Raut, Chandrajit P. ;

Roets, Evelyne ;

Sandrucci, Sergio ;

Sbaraglia, Marta ;

Stacchiotti, Silvia ;

Thornton, Katherine A. ;

van der Graaf, Winette ;

van der Zande, Kim ;

van Houdt, Winan J. .

EUROPEAN JOURNAL OF CANCER, 2020, 127 :96-107

[9] Neoadjuvant and adjuvant strategies in retroperitoneal sarcoma [J].

Almond, L. Max ;

Gronchi, Alessandro ;

Strauss, Dirk ;

Jafri, Mariam ;

Ford, Samuel ;

Desai, Anant .

EJSO, 2018, 44 (05) :571-579

[10] The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more "personalized" approach to cancer staging [J].

Amin, Mahul B. ;

Greene, Frederick L. ;

Edge, Stephen B. ;

Compton, Carolyn C. ;

Gershenwald, Jeffrey E. ;

Brookland, Robert K. ;

Meyer, Laura ;

Gress, Donna M. ;

Byrd, David R. ;

Winchester, David P. .

CA-A CANCER JOURNAL FOR CLINICIANS, 2017, 67 (02) :93-99

← 1 2 3 4 5 6 7 8 9 10 →