Combinational light emitting diode-high frequency focused ultrasound treatment for HeLa cell

被引：6

作者：

Choe, Se-Woon ^{[1
]}

Park, Kitae ^{[1
]}

Park, Chulwoo ^{[1
]}

Ryu, Jaemyung ^{[2
]}

Choi, Hojong ^{[1
]}

机构：

[1] Kumoh Natl Inst Technol, Dept Med IT Convergence Engn, Gumi, South Korea

[2] Kumoh Natl Inst Technol, Dept Opt Syst Engn, Gumi, South Korea

来源：

COMPUTER ASSISTED SURGERY | 2017年 / 22卷

基金：

新加坡国家研究基金会;

关键词：

Light emitting diode; high frequency focused ultrasound; HeLa cell; cancer treatment introduction; CANCER-CELLS; PHOTOTHERAPY; THERAPY; IRRADIATION; SKIN;

D O I：

10.1080/24699322.2017.1379158

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Purpose: Light sources such as laser and light emitting diode or ultrasound devices have been widely used for cancer therapy and regenerative medicines, since they are more cost-effective and less harmful than radiation therapy, chemotherapy or magnetic treatment. Compared to laser and low intensity ultrasound techniques, light emitting diode and high frequency focused ultrasound shows enhanced therapeutic effects, especially for small tumors. Materials and methods: We propose combinational light emitting diode-high frequency focused ultrasound treatment for human cervical cancer HeLa cells. Individual red, green, and blue light emitting diode light only, high frequency focused ultrasound only, or light emitting diode light combined with high frequency focused ultrasound treatments were applied in order to characterize the responses of HeLa cells. Results: Cell density exposed by blue light emitting diode light combined with high frequency focused ultrasound (2.19 +/- 0.58%) was much lower than that of cells exposed by red and green light emitting diode lights (81.71 +/- 9.92% and 61.81 +/- 4.09%), blue light emitting diode light (11.19 +/- 2.51%) or high frequency focused ultrasound only (9.72 +/- 1.04%). Conclusions: We believe that the proposed combinational blue light emitting diode-high frequency focused ultrasound treatment could have therapeutic benefits to alleviate cancer cell proliferation

引用

页码：79 / 85

页数：7

共 27 条

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