A Peptide Produced by Pseudomonas tolaasi, Tolaasin Binds to Metal Ions

被引：5

作者：

Lee, Sunhee ^{[1
]}

Jo, Geunhyeong ^{[1
]}

Hwang, Doseok ^{[1
]}

Woo, Yoonkyung ^{[1
]}

Lee, Younggiu ^{[1
]}

Yong, Yeonjoong ^{[1
]}

Kang, Kyungrai ^{[1
]}

Hyun, Jiye ^{[1
]}

Kim, Young-Kee ^{[2
]}

Kim, Dong-Woon ^{[3
]}

Lim, Yoongho ^{[1
]}

机构：

[1] Konkuk Univ, RCD, BMIC, Div Biosci & Biotechnol, Seoul 143701, South Korea

[2] Chungbuk Natl Univ, Dept Agr Chem, Chungbuk 361763, South Korea

[3] RDA, Natl Inst Anim Sci, Swine Sci Div, Cheonan 330801, South Korea

来源：

JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY | 2011年 / 54卷 / 04期

基金：

新加坡国家研究基金会;

关键词：

calcium ion; Pseudomonas tolaasi; sodium ion; tolaasin; zinc ion; TOXIN; LIPODEPSIPEPTIDES; MUSHROOM;

D O I：

10.3839/jksabc.2011.096

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Brown blotch disease in mushrooms is caused by Pseudomonas tolaasin, which produces a peptide toxin, tolaasin 1, and zinc ion inhibits the channel formed by tolaasin I. NMR experiments revealed that zinc, sodium, and calcium ions can bind to tolaasin 1 and their binding position on tolaasin I is the lactone ring.

引用

页码：633 / 636

页数：4