THE EXPRESSION OF MUSCLE ANKYRIN REPEAT PROTEINS IN BROWN ADIPOSE TISSUE

被引:0
|
作者
Rakicevic, Ljiljana [1 ]
Petrovic, Natasa [2 ]
Radojkovic, Dragica [1 ]
Kojic, Snezana [1 ]
机构
[1] Univ Belgrade, Inst Mol Genet & Genet Engn, Belgrade 11010, Serbia
[2] Stockholm Univ, Wenner Gren Inst, SE-10691 Stockholm, Sweden
关键词
MARP family; brown adipose tissue; ACTIVATED RECEPTOR-GAMMA; SKELETAL-MUSCLE; GENE-EXPRESSION; PPAR-GAMMA; INSULIN-RESISTANCE; NUCLEAR-PROTEIN; ADULT HUMANS; ANKRD2; IDENTIFICATION; ADIPOCYTES;
D O I
10.2298/ABS1104915R
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
MARP family members CARP, Ankrd2 and DARP are expressed in the striated muscle, while DARP protein is also detected in brown adipose tissue (BAT). Taking into account recent findings concerning the common origin of muscle and brown fat, expression of CARP and Ankrd2 in mouse BAT was investigated. We demonstrated Ankrd2 expression in both inactive and thermogenically active BAT, while CARP expression was not detected. Our findings suggest that the expression of Ankrd2 in BAT could be a part of the "myogenic transcriptional signature", further supporting the evidence that muscle and brown adipose cells arise from the same myoblastic precursor.
引用
收藏
页码:915 / 920
页数:6
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