AN EVALUATION OF ANTIOXIDANT, ANTIMICROBIAL, ANTIBIOFILM AND CYTOTOXIC ACTIVITIES OF FIVE VERBASCUM SPECIES IN TURKEY

被引：10

作者：

Sen-Utsukarci, Burcu ^{[1
]}

Doslerz, Sibel ^{[2
]}

Taskin, Turgut ^{[3
]}

Abudayyak, Mahmoud ^{[4
]}

Ozhan, Gul ^{[5
]}

Mat, Afife ^{[1
]}

机构：

[1] Istanbul Univ, Fac Pharm, Dept Pharmacognosy, TR-34116 Istanbul, Turkey

[2] Istanbul Univ, Fac Pharm, Dept Pharmaceut Microbiol, TR-34116 Istanbul, Turkey

[3] Marmara Univ, Fac Pharm, Dept Pharmacognosy, TR-34668 Istanbul, Turkey

[4] Karadeniz Tech Univ, Fac Pharm, Dept Pharmaceut Toxicol, TR-61000 Trabzon, Turkey

[5] Istanbul Univ, Fac Pharm, Dept Pharmaceut Toxicol, TR-34116 Istanbul, Turkey

来源：

FARMACIA | 2018年 / 66卷 / 06期

关键词：

Verbascum species; antioxidant; antimicrobial; antibiofilm; cytotoxicity; food preservation; SUPPLEMENT FLORA; ADDITIONAL TAXA; MEDICINAL-PLANTS; CHECKLIST; XANTHOPHOENICEUM; ANTIBACTERIAL; CONSTITUENTS; EXTRACTS; GROWTH;

D O I：

10.31925/FARMACIA.2018.6.14

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Verbascum L. species are used for different medicinal purposes in Turkish folk medicine such as diuretic, expectorant, laxative, mucolytic, sedative, sudorific, and wound healer. Five Verbascum species, two of which are used in medicine, were investigated for their antimicrobial, antioxidant and cytotoxic activities. Determination of the total phenolic compounds, DPPH and ABTS methods were preferred for the antioxidant tests. The antimicrobial and antibiofilm activities of the extracts, which were not studied previously, were investigated against pathogenic and potential pathogenic agents. The cytotoxicity was assessed by MTT and LDH tests. This study is very important for finding new therapeutic sources and also new, natural sources for food preservation.

引用

页码：1014 / 1020

页数：7

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