Supramolecular delivery of fluorescent probes in developing embryos

被引:9
|
作者
Zhang, Yang
Thapaliya, Ek Raj
Tang, Sicheng
Baker, James D.
Raymo, Francisco M. [1 ]
机构
[1] Univ Miami, Lab Mol Photon, Dept Biol, 1301 Mem Dr, Coral Gables, FL 33146 USA
来源
RSC ADVANCES | 2016年 / 6卷 / 76期
基金
美国国家科学基金会;
关键词
NANOCARRIERS; TECHNOLOGIES; CARGO;
D O I
10.1039/c6ra15368b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Self-assembling nanocarriers of amphiphilic polymers encapsulate hydrophobic fluorophores in their hydrophobic interior and, upon injection in Drosophila melanogaster embryos, release their cargo into the cellular blastoderm. The fluorescence of the delivered probes can be detected immediately upon injection to allow the visualization of the very early stages of embryogenesis.
引用
收藏
页码:72756 / 72760
页数:5
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