B-alkylcatecholboranes as a source of radicals for efficient conjugate additions and allylations

被引：21

作者：

Schaffner, AP ^{[1
]}

Becattini, B ^{[1
]}

Ollivier, C ^{[1
]}

Weber, V ^{[1
]}

Renaud, P ^{[1
]}

机构：

[1] Univ Bern, Dept Chem & Biochem, CH-3000 Bern 9, Switzerland

来源：

SYNTHESIS-STUTTGART | 2003年 / 17期

关键词：

radicals; tin-free; hydroboration; allylation; conjugate addition;

D O I：

10.1055/s-2003-42430

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

B-Alkylcatecholboranes, easily prepared in situ by hydroboration of alkenes, are powerful radical precursors that can be used for carbon-carbon bond formation. Typical procedures for (a) conjugate addition to enones, (b) conjugate addition to activated alkenes such as vinyl sulfones, and (c) direct allylation are described. Experimentally, these three one-pot reactions are easy to perform. No slow addition of a reagent, a procedure frequently encountered in intermolecular radical additions, is required.

引用

页码：2740 / 2742

页数：3

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