Treatment of hyperferritinemia

被引：34

作者：

Beaton, Melanie D. ^{[1
]}

Adams, Paul C. ^{[1
]}

机构：

[1] Univ Western Ontario, London Hlth Sci Ctr, Dept Med, Div Gastroenterol, London, ON N6A 5A5, Canada

来源：

ANNALS OF HEPATOLOGY | 2012年 / 11卷 / 03期

关键词：

Iron overload; Ferritin; Liver Disease; Therapy; FATTY LIVER-DISEASE; BODY IRON STORES; SERUM FERRITIN; HEPATOCELLULAR-CARCINOMA; METABOLIC SYNDROME; TRANSFERRIN SATURATION; OXIDATIVE STRESS; HEMOCHROMATOSIS; OVERLOAD; RISK;

D O I：

10.1016/S1665-2681(19)30923-8

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Elevated serum ferritin, or hyperferritinemia, is a common finding on routine bloodwork and often prompts referral for further evaluation. In the following review, we outline the various causes of hyperferritinemia and point out that, in the majority of cases, this does not represent true iron overload. Despite much research interest in this area, the precise mechanism of hyperferritinemia and its impact on disease severity in various clinical conditions continues to be debated. While some research suggests that iron reduction in cases of hyperferritinemia is of benefit, the decision to treat such patients should be individualized, and may be influenced by the presence of other features of iron overload.

引用

页码：294 / 300

页数：7

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