Reducing LDL with PCSK9 Inhibitors - The Clinical Benefit of Lipid Drugs

被引:109
作者
Everett, Brendan M. [1 ,2 ]
Smith, Robert J. [3 ,4 ,5 ]
Hiatt, William R. [6 ,7 ]
机构
[1] Harvard Univ, Sch Med, Boston, MA 02138 USA
[2] Brigham & Womens Hosp, Div Cardiovasc & Prevent Med, Dept Med, Boston, MA 02115 USA
[3] Brown Univ, Dept Med, Alpert Med Sch, Providence, RI 02912 USA
[4] Brown Univ, Dept Hlth Serv Policy & Practice, Sch Publ Hlth, Providence, RI 02912 USA
[5] Providence VA Med Ctr, Ocean State Res Inst, Providence, RI 02912 USA
[6] Univ Colorado, Sch Med, Dept Med, Div Cardiol, Aurora, CO USA
[7] CPC Clin Res, Aurora, CO USA
关键词
HIGH-RISK; THERAPY; EVENTS; TRIAL;
D O I
10.1056/NEJMp1508120
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1588 / 1591
页数:4
相关论文
共 5 条
[1]   Effects of torcetrapib in patients at high risk for coronary events [J].
Barter, Philip J. ;
Caulfield, Mark ;
Eriksson, Mats ;
Grundy, Scott M. ;
Kastelein, John J. P. ;
Komajda, Michel ;
Lopez-Sendon, Jose ;
Mosca, Lori ;
Tardif, Jean-Claude ;
Waters, David D. ;
Shear, Charles L. ;
Revkin, James H. ;
Buhr, Kevin A. ;
Fisher, Marian R. ;
Tall, Alan R. ;
Brewer, Bryan .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (21) :2109-2122
[2]   Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes [J].
Cannon, Christopher P. ;
Blazing, Michael A. ;
Giugliano, Robert P. ;
McCagg, Amy ;
White, Jennifer A. ;
Theroux, Pierre ;
Darius, Harald ;
Lewis, Basil S. ;
Ophuis, Ton Oude ;
Jukema, J. Wouter ;
De Ferrari, Gaetano M. ;
Ruzyllo, Witold ;
De Lucca, Paul ;
Im, KyungAh ;
Bohula, Erin A. ;
Reist, Craig ;
Wiviott, Stephen D. ;
Tershakovec, Andrew M. ;
Musliner, Thomas A. ;
Braunwald, Eugene ;
Califf, Robert M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (25) :2387-2397
[3]   Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women [J].
Hulley, S ;
Grady, D ;
Bush, T ;
Furberg, C ;
Herrington, D ;
Riggs, B ;
Vittinghoff, E .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (07) :605-613
[4]   Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study):: randomised controlled trial [J].
Keech, A ;
Simes, RJ ;
Barter, P ;
Best, J ;
Scott, R ;
Taskinen, MR ;
Forder, P ;
Pillai, A ;
Davis, T ;
Glasziou, P ;
Drury, P ;
Kesäniemi, YA ;
Sullivan, D ;
Hunt, D ;
Colman, P ;
d'Emden, M ;
Whiting, M ;
Ehnholm, C ;
Laakso, M .
LANCET, 2005, 366 (9500) :1849-1861
[5]   Effects of Extended-Release Niacin with Laropiprant in High-Risk Patients [J].
Landray, Martin J. ;
Haynes, Richard ;
Hopewell, Jemma C. ;
Parish, Sarah ;
Aung, Theingi ;
Tomson, Joseph ;
Wallendszus, Karl ;
Craig, Martin ;
Jiang, Lixin ;
Collins, Rory ;
Armitage, Jane .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (03) :203-212