Paleo-Eskimo mtDNA genome reveals matrilineal discontinuity in Greenland

被引：137

作者：

Gilbert, M. Thomas P. ^{[1
]}

Kivisild, Toomas ^{[2
]}

Gronnow, Bjarne ^{[3
]}

Andersen, Pernille K. ^{[4
]}

Metspalu, Ene ^{[5
,6
]}

Reidla, Maere ^{[5
,6
]}

Tamm, Erika ^{[5
,6
]}

Axelsson, Erik ^{[1
]}

Gotherstrom, Anders ^{[7
]}

Campos, Paula F. ^{[1
]}

Rasmussen, Morten ^{[1
]}

Metspalu, Mait ^{[5
,6
]}

Higham, Thomas F. G. ^{[8
]}

Schwenninger, Jean-Luc ^{[8
]}

Nathan, Roger ^{[8
]}

De Hoog, Cees-Jan ^{[9
]}

Koch, Anders ^{[10
]}

Moller, Lone Nukaaraq ^{[11
]}

Andreasen, Claus ^{[12
]}

Meldgaard, Morten ^{[13
]}

Villems, Richard ^{[5
,6
]}

Bendixen, Christian ^{[4
]}

Willerslev, Eske ^{[1
]}

机构：

[1] Univ Copenhagen, Dept Biol, Ctr Ancient Genet, DK-2100 Copenhagen, Denmark

[2] Univ Cambridge, Leverhulme Ctr Human Evolutionary Studies, Cambridge CB2 1QH, England

[3] Natl Museum Denmark, SILA Greenland Res Ctr, DK-1220 Copenhagen, Denmark

[4] Univ Aarhus, Fac Agr Sci, Dept Genet & Biotechnol, DK-8830 Tjele, Denmark

[5] Univ Tartu, Dept Evolut Biol, EE-51010 Tartu, Estonia

[6] Estonian Bioctr, EE-51010 Tartu, Estonia

[7] Uppsala Univ, Dept Evolut Biol, S-74236 Uppsala, Sweden

[8] Univ Oxford, Archaeol & Hist Art Res Lab, Oxford OX1 3QY, England

[9] Univ Oxford, Dept Earth Sci, Oxford OX1 3PR, England

[10] Statens Serum Inst, Dept Epidemiol Res, DK-2300 Copenhagen, Denmark

[11] Univ Copenhagen, Danish Ctr Expt Parasitol, Dept Vet Pathobiol, Fac Life Sci, DK-1870 Frederiksberg C, Denmark

[12] Greenland Natl Museum & Archives, Nuuk 3900, Greenland

[13] Geologisk Museum, Natl Hist Museum Denmark, DK-1350 Copenhagen, Denmark

来源：

SCIENCE | 2008年 / 320卷 / 5884期

关键词：

D O I：

10.1126/science.1159750

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The Paleo- Eskimo Saqqaq and Independence I cultures, documented from archaeological remains in Northern Canada and Greenland, represent the earliest human expansion into the New World's northern extremes. However, their origin and genetic relationship to later cultures are unknown. We sequenced a mitochondrial genome from a Paleo- Eskimo human by using 3400- to 4500- year- old frozen hair excavated from an early Greenlandic Saqqaq settlement. The sample is distinct from modern Native Americans and Neo- Eskimos, falling within haplogroup D2a1, a group previously observed among modern Aleuts and Siberian Sireniki Yuit. This result suggests that the earliest migrants into the New World's northern extremes derived from populations in the Bering Sea area and were not directly related to Native Americans or the later Neo- Eskimos that replaced them.

引用

页码：1787 / 1789

页数：3

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