68Ga-FAPI Versus 18F-FDG PET/CT in Recurrent Undifferentiated Pleomorphic Sarcoma of Colon Mesentery

被引:2
作者
Zhang, Linqi [1 ]
Liu, Zhidong [1 ]
Jiang, Shuqin [1 ]
He, Qiao [2 ]
Zhang, Rusen [1 ]
机构
[1] Guangzhou Med Univ, Affiliated Canc Hosp & Inst, Dept Nucl Med, 78 Hengzhigang Rd, Guangzhou 510095, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Nucl Med, Guangzhou, Peoples R China
基金
中国国家自然科学基金;
关键词
undifferentiated pleomorphic sarcoma; colon mesentery; Ga-68-FAPI; F-18-FDG; PET/CT;
D O I
10.1097/RLU.0000000000004275
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A 56-year-old woman presented with primary undifferentiated pleomorphic sarcoma of colon mesentery underwent complete surgical resection approximately 7 months ago. Abdominal contrast-enhanced CT showed a new mass in the descending colon, suggesting a high probability of tumor recurrence. Under a clinical trial, the patient underwent Ga-68-FAPI and F-18-FDG PET/CT to detect whether there are additional recurrent lesions. Compared with F-18-FDG PET/CT, the recurrent undifferentiated pleomorphic sarcoma of colon mesentery, peritoneum, pelvic lymph node, and lung metastases showed higher uptake in Ga-68-FAPI PET/CT. This case showed that Ga-68-FAPI might be a promising radiopharmaceutical in the evaluation of undifferentiated pleomorphic sarcoma.
引用
收藏
页码:E651 / E653
页数:3
相关论文
共 8 条
[1]   Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours [J].
Dohi, Osamu ;
Ohtani, Haruo ;
Hatori, Masahito ;
Sato, Elichi ;
Hosaka, Masami ;
Nagura, Hiroshi ;
Itoi, Eiji ;
Kokubun, Shoichi .
HISTOPATHOLOGY, 2009, 55 (04) :432-440
[2]   Head-to-head evaluation of [18F]FDG and [68 Ga]Ga-DOTA-FAPI-04 PET/CT in recurrent soft tissue sarcoma [J].
Gu, Bingxin ;
Liu, Xin ;
Wang, Shuoer ;
Xu, Xiaoping ;
Liu, Xiaosheng ;
Hu, Silong ;
Yan, Wangjun ;
Luo, Zhiguo ;
Song, Shaoli .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022, 49 (08) :2889-2901
[3]   18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT Findings of Abdominal Leiomyosarcoma [J].
Guzel, Yunus ;
Can, Canan ;
Sogutcu, Nilgun ;
Gundes, Ebubekir ;
Gundogan, Cihan .
CLINICAL NUCLEAR MEDICINE, 2021, 46 (12) :E594-E597
[4]   68Ga-FAPI as a Diagnostic Tool in Sarcoma: Data from the 68Ga-FAPI PET Prospective Observational Trial [J].
Kessler, Lukas ;
Ferdinandus, Justin ;
Hirmas, Nader ;
Bauer, Sebastian ;
Dirksen, Uta ;
Zarrad, Fadi ;
Nader, Michael ;
Chodyla, Michal ;
Milosevic, Aleksandar ;
Umutlu, Lale ;
Schuler, Martin ;
Podleska, Lars Erik ;
Schildhaus, Hans-Ulrich ;
Fendler, Wolfgang P. ;
Hamacher, Rainer .
JOURNAL OF NUCLEAR MEDICINE, 2022, 63 (01) :89-95
[5]   Novel FAP ligands enable improved imaging contrast in sarcoma patients due to FAPI-PET/CT [J].
Koerber, Stefan A. ;
Finck, R. ;
Dendl, K. ;
Uhl, M. ;
Lindner, T. ;
Kratochwil, C. ;
Roehrich, M. ;
Rathke, H. ;
Ungerechts, G. ;
Adeberg, S. ;
Herfarth, K. ;
Jaeger, D. ;
Debus, J. ;
Haberkorn, U. ;
Giesel, F. L. .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2021, 48 (12) :3918-3924
[6]   Primary Undifferentiated Pleomorphic Sarcoma of the Colon Mesentery [J].
Lee, Joo Hyun ;
Kang, Dong Baek ;
Park, Won Cheol .
ANNALS OF COLOPROCTOLOGY, 2019, 35 (03) :152-154
[7]   Biology and Management of Undifferentiated Pleomorphic Sarcoma, Myxofibrosarcoma, and Malignant Peripheral Nerve Sheath Tumors: State of the Art and Perspectives [J].
Widemann, Brigitte C. ;
Italiano, Antoine .
JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (02) :160-+
[8]  
Zambo Iva, 2014, Cesk Patol, V50, P64