Micro- and nanotechnology in cardiovascular tissue engineering

被引：49

作者：

Zhang, Boyang ^{[1
,2
]}

Xiao, Yun ^{[1
,2
]}

Hsieh, Anne ^{[1
,2
]}

Thavandiran, Nimalan ^{[1
,2
]}

Radisic, Milica ^{[1
,2
,3
]}

机构：

[1] Univ Toronto, Dept Chem Engn & Appl Chem, Toronto, ON M5S 3G9, Canada

[2] Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3G9, Canada

[3] Univ Toronto, Heart & Stroke Richard Lewar Ctr Excellence, Toronto, ON M5S 3G9, Canada

来源：

NANOTECHNOLOGY | 2011年 / 22卷 / 49期

基金：

加拿大自然科学与工程研究理事会;

关键词：

CARDIAC TISSUE; SUBSTRATE STIFFNESS; SOFT LITHOGRAPHY; FABRICATION; SCAFFOLDS; CULTURE; FORCE; SIZE; DIFFERENTIATION; GENERATION;

D O I：

10.1088/0957-4484/22/49/494003

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

While in nature the formation of complex tissues is gradually shaped by the long journey of development, in tissue engineering constructing complex tissues relies heavily on our ability to directly manipulate and control the micro-cellular environment in vitro. Not surprisingly, advancements in both microfabrication and nanofabrication have powered the field of tissue engineering in many aspects. Focusing on cardiac tissue engineering, this paper highlights the applications of fabrication techniques in various aspects of tissue engineering research: (1) cell responses to micro-and nanopatterned topographical cues, (2) cell responses to patterned biochemical cues, (3) controlled 3D scaffolds, (4) patterned tissue vascularization and (5) electromechanical regulation of tissue assembly and function.

引用

页数：10

共 85 条

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