Nitric oxide in the regulation of body temperature and fever

被引：46
|
作者：
Steiner, AA
Branco, LGS [1 ]
机构：
[1] Univ Sao Paulo, Dent Sch Ribeirao Preto, BR-14040904 Ribeirao Preto, SP, Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, BR-14040904 Ribeirao Preto, SP, Brazil
来源：
JOURNAL OF THERMAL BIOLOGY | 2001年 / 26卷 / 4-5期
基金：
巴西圣保罗研究基金会;
关键词：
nitric oxide; nitric oxide synthase; body temperature; thermoregulation; fever; central nervous system; set point; acute phase reaction;
D O I：
10.1016/S0306-4565(01)00038-9
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
(1) In this article, the aspects regarding the role of nitric oxide (NO) in thermoregulation and fever is reviewed. (2) It is currently believed that fever results from dc novo synthesis of cytokines and subsequent stimulation of the generation of prostaglandins in the central nervous system. However, the mechanisms underlying fever still remain only partly understood. (3) Recently, a new biologically active molecule has been described, i.e., the gaseous Compound NO. This molecule started a revolution in the understanding of several physiological and pathophysiological processes, including thermoregulation and fever. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：325 / 330
页数：6
相关论文
共 50 条
  • [41] Nitric Oxide Synthase Neurons in the Preoptic Hypothalamus Are NREM and REM Sleep-Active and Lower Body Temperature
    Harding, Edward C.
    Ba, Wei
    Zahir, Reesha
    Yu, Xiao
    Yustos, Raquel
    Hsieh, Bryan
    Lignos, Leda
    Vyssotski, Alexei L.
    Merkle, Florian T.
    Constandinou, Timothy G.
    Franks, Nicholas P.
    Wisden, William
    FRONTIERS IN NEUROSCIENCE, 2021, 15
  • [42] cGMP-mediated negative-feedback regulation of endothelial nitric oxide synthase expression by nitric oxide
    Vaziri, ND
    Wang, XQ
    HYPERTENSION, 1999, 34 (06) : 1237 - 1241
  • [43] Effects of a neuronal nitric oxide synthase inhibitor on lipopolysaccharide-induced fever
    Perotti, CAA
    Nogueira, MS
    Antunes-Rodrigues, J
    Cárnio, EC
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 1999, 32 (11) : 1381 - 1387
  • [44] Nitric oxide synthase production and nitric oxide regulation of preimplantation embryo development
    Tranguch, S
    Steuerwald, N
    Huet-Hudson, YA
    BIOLOGY OF REPRODUCTION, 2003, 68 (05) : 1538 - 1544
  • [45] Nitric oxide and carotid body chemoreception
    Iturriaga, R
    BIOLOGICAL RESEARCH, 2001, 34 (02) : 135 - 139
  • [46] The nitric oxide pathway is an important modulator of stress-induced fever in rats
    De Paula, D
    Steiner, AA
    Branco, LGS
    PHYSIOLOGY & BEHAVIOR, 2000, 70 (05) : 505 - 511
  • [47] Involvement of purinergic signalling in central mechanisms of body temperature regulation in rats
    Gourine, AV
    Melenchuk, EV
    Poputnikov, DM
    Gourine, VN
    Spyer, KM
    BRITISH JOURNAL OF PHARMACOLOGY, 2002, 135 (08) : 2047 - 2055
  • [48] NITRIC-OXIDE IN THE SENSORY FUNCTION OF THE CAROTID-BODY
    PRABHAKAR, NR
    KUMAR, GK
    CHANG, CH
    AGANI, FH
    HAXHIU, MA
    BRAIN RESEARCH, 1993, 625 (01) : 16 - 22
  • [49] Regulation of gene expression by nitric oxide
    Pfeilschifter, J
    Eberhardt, W
    Beck, KF
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2001, 442 (04): : 479 - 486
  • [50] Regulation of nitric oxide generation and consumption
    Abu-Soud, Husam M.
    Camp, Olivia G.
    Ramadoss, Jayanth
    Chatzicharalampous, Charalampos
    Kofinas, George
    Kofinas, Jason
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2025, 21 (03): : 1097 - 1109
12345