AIDS-related primary central nervous system lymphoma

被引:33
作者
Kasamon, YL [1 ]
Ambinder, RF [1 ]
机构
[1] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Div Hematol Malignancies, Baltimore, MD 21231 USA
关键词
D O I
10.1016/j.hoc.2005.05.004
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Primary central nervous system lymphoma (PCNSL) can develop in the setting of profound immunosuppression, including late-stage infection with HIV. The management of such patients has yet to be defined optimally and differs substantially from that of immunocompetent patients who have PCNSL. The clinical features, diagnosis, and management of AIDS-related PCNSL are reviewed. The authors focus on commonly encountered diagnostic and therapeutic dilemmas and explore some promises and pitfalls of Epstein-Barr virus-directed therapies.
引用
收藏
页码:665 / +
页数:25
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