Binding of phosphoproteins to the regulatory region of the mouse protamine 2 promoter

被引：0
作者：
JungHa, HS
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来源：
MOLECULES AND CELLS | 1996年 / 6卷 / 02期
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暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
To understand the transcriptional regulation of the mouse protamine 2 gene, the interactions between nuclear proteins and promoter DNA of the regulatory region was investigated. Within the promoter region, - 170 to + 8, two protein binding sites were identified. Site 1, - 64 to - 48, contained a, cAMP responsive element, CRE, and site 2, - 87 to - 67, contained a CAAT-like element. In vitro phosphorylation of testis nuclear proteins increased the binding affinities for these two sites and also transcriptional activity of the mouse protamine 2 promoter.
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页码：221 / 224
页数：4
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