Uterine tumors resembling ovarian sex cord-stromal tumors: synchronous uterine tumors resembling ovarian sex cord-stromal tumors and ovarian sex cord tumor
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Abdullazade, Samir
Kosemehmetoglu, Kemal
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机构:Hacettepe Univ, Fac Med, Dept Pathol, TR-06100 Ankara, Turkey
Kosemehmetoglu, Kemal
Adanir, Ilknur
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Hacettepe Univ, Dept Obstet & Gynecol, TR-06100 Ankara, TurkeyHacettepe Univ, Fac Med, Dept Pathol, TR-06100 Ankara, Turkey
Adanir, Ilknur
[2
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Kutluay, Lale
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Genel Pathol Ctr, TR-06440 Ankara, TurkeyHacettepe Univ, Fac Med, Dept Pathol, TR-06100 Ankara, Turkey
Kutluay, Lale
[3
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Usubutun, Alp
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Hacettepe Univ, Fac Med, Dept Pathol, TR-06100 Ankara, TurkeyHacettepe Univ, Fac Med, Dept Pathol, TR-06100 Ankara, Turkey
Usubutun, Alp
[1
]
机构:
[1] Hacettepe Univ, Fac Med, Dept Pathol, TR-06100 Ankara, Turkey
[2] Hacettepe Univ, Dept Obstet & Gynecol, TR-06100 Ankara, Turkey
Uterine tumors resembling ovarian sex cord-stromal tumors (UTROSCTs) are very rare. In this article, we present 3 cases that manifest classical histomorphological features alongside diverse immunohistochemical findings. As a distinctive finding, one of the patients had UTROSCT in the uterus and an ovarian sex cord tumor, called granulosa cell tumor, in the left ovary, simultaneously. Problems in diagnosing such pathologic condition generally arise because of the variable histologic picture of UTROSCT and may cause problems for general and other nongynecologic surgical pathologists. Immunohistochemically, these tumors express different markers that indicate their polyphenotypic origins. (C) 2010 Elsevier Inc. All rights reserved.