Transplantation of cultured human neural stem cells in rabbits with experimental laser-induced damage to the retina

被引:12
作者
Pak, NV [1 ]
Podgornyi, OV
Aleksandrova, MA
Chentsova, EV
Ivanov, AN
Golubeva, ON
Poltavtseva, RA
Marey, MV
Sukhikh, GT
机构
[1] Minist Publ Hlth Russia, Chelmgolts Moscow Res Inst Eye Dis, Moscow, Russia
[2] Russian Acad Sci, NK Koltsov Dev Biol Inst, Moscow 117901, Russia
[3] Russian Acad Sci, Inst Gene Biol, Moscow 117901, Russia
[4] Russian Acad Med Sci, Res CtrObstet Gynecol & Perinatol, Moscow, Russia
关键词
human neural stem/progenitor cells; retina; laser damage; xenotransplantation; immunohistochemistry;
D O I
10.1007/s10517-005-0087-7
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Cultured neural stem/progenitor cells from human fetal brain were transplanted into the retrobulbar and suprachoroid space in rabbits with laser-induced damage to the retina. Transplanted cells survived, retained multipotent activity, migrated into the zone of injury, and stimulated reparation and regeneration in the traumatized retina.
引用
收藏
页码:525 / 528
页数:4
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