Ribozymes: The hammerhead swings into action

被引：9
|
作者：
Doudna, JA [1 ]
机构：
[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA
[2] Yale Univ, Howard Hughes Med Inst, New Haven, CT 06520 USA
来源：
CURRENT BIOLOGY | 1998年 / 8卷 / 14期
关键词：
D O I：
10.1016/S0960-9822(98)70316-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new crystal structure of a modified hammerhead ribozyme reveals an intermediate conformation that may explain discrepancies between previous structures and the required orientation of the labile bond in the ribozyme's active site.
引用
收藏
页码：R495 / R497
页数：3
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