The on-line preconcentration of nanoparticles in electromigration techniques

被引：8

作者：

Dziomba, Szymon ^{[1
]}

Ciura, Krzesimir ^{[2
]}

Dawid, Marta ^{[1
]}

机构：

[1] Med Univ Gdansk, Fac Pharm, Dept Toxicol, 107 Hallera St, PL-80416 Gdansk, Poland

[2] Med Univ Gdansk, Fac Pharm, Dept Phys Chem, 107 Hallera St, PL-80416 Gdansk, Poland

来源：

JOURNAL OF CHROMATOGRAPHY A | 2019年 / 1606卷

关键词：

Capillary electrophoresis; Isotachophoresis; Microchip; Nanoparticles; Preconcentration; Stacking; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; CORE-SHELL NANOPARTICLES; POLARITY STACKING MODE; CAPILLARY-ELECTROPHORESIS; GOLD NANOPARTICLES; MAGNETITE CORE; SILVER NANOPARTICLES; RADIUS DISTRIBUTION; MIXED MICELLES; SEPARATION;

D O I：

10.1016/j.chroma.2019.06.053

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Electromigration techniques have recently emerged as an alternative analytical tool for nanoparticles characterization. Due to the high throughput capability and separation efficiency their application for detection/quantification of nanomaterials in samples of various origin has attracted much attention. While the electromigration techniques are known to suffer from insufficient detection sensitivity, a number of papers investigating on-line preconcentration of nanoparticles in capillary electrophoresis was addressed to the issue. In this work the available literature on nanoparticles stacking in electrodriven separation techniques was reviewed. The discussion was supported by theoretical background. A special emphasis was put on the stability of nanoparticles dispersion during electrophoretic process. The considerations on future perspectives were included in final remarks. (C) 2019 Elsevier B.v. All rights reserved.

引用

页数：9

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[21] Microfluidics-based on-a-chip systems for isolating and analysing extracellular vesicles [J].