Frequency and duration of phototherapy in preterm infants <35 weeks gestation

被引：20
作者：
Mukherjee, Devashis [1 ]
Coffey, Mary [2 ]
Maisels, M. Jeffrey [1 ]
机构：
[1] Oakland Univ, William Beaumont Sch Med, Beaumont Childrens Hosp, Royal Oak, MI 48067 USA
[2] Beaumont Hlth, Biostat, Res Inst, Royal Oak, MI USA
来源：
JOURNAL OF PERINATOLOGY | 2018年 / 38卷 / 09期
关键词：
AFFECTS CYTOKINE PRODUCTION; LOW-BIRTH-WEIGHT; NEONATAL JAUNDICE; DNA-DAMAGE; HYPERBILIRUBINEMIA; NEWBORNS; RISK; LEUKEMIA; LESS;
D O I：
10.1038/s41372-018-0153-4
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective To evaluate the frequency, age at phototherapy (PT) initiation, and duration of PT use in infants 23(0/7) to 34(6/7) weeks of gestation in two neonatal intensive care units (NICUs) over 4 time periods. Study design We reviewed the charts of all infants born at 23(0/7)-34(6/7) weeks of gestational age (GA) and admitted to the NICUs of two hospitals between January 2009 and September 2015. We calculated the proportion of infants who received PT and the total duration of PT exposure. Results Overall 2023 (81.8%) received PT, and PT use was inversely related to GA and birthweight. More infants received PT when GA was added as a criterion for initiating PT. The median duration (interquartile range (IQR)) of PT for all infants was 50 (27-85) h and in the lowest GA group was 74 (42-111) h. Conclusions Recent US consensus guidelines appear to have led to an increased use of PT in our NICUs and studies from Norway indicate that we use PT considerably more frequently and for longer durations than do our Norwegian colleagues.
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页码：1246 / 1251
页数：6
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