Changes in cardiorespiratory fitness through adolescence predict metabolic syndrome in young adults

被引:17
|
作者
Maestu, Evelin [1 ]
Harro, Jaanus [2 ]
Veidebaum, Toomas [3 ]
Kurrikoff, Triin [4 ]
Jurimae, Jaak [1 ]
Maestu, Jarek [1 ]
机构
[1] Univ Tartu, Fac Med, Inst Sport Sci & Physiotherapy, Dept Exercise Biol, Tartu, Estonia
[2] Univ Tartu, Fac Social Sci, Inst Psychol, Dept Neuropsychopharmacol, Tartu, Estonia
[3] Natl Inst Hlth Dev, Tallinn, Estonia
[4] Univ Tartu, Fac Social Sci, Inst Social Studies, Tartu, Estonia
关键词
Cardiorespiratory fitness; Cohort study; Metabolic syndrome risk factors; Metabolic health; Young adulthood; CARDIOVASCULAR RISK-FACTORS; ALL-CAUSE MORTALITY; PHYSICAL-ACTIVITY; CHILDHOOD; HEALTH; ADIPOSITY; CHILDREN; FATNESS; ASSOCIATIONS; OBESITY;
D O I
10.1016/j.numecd.2019.12.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and aims: Higher cardiorespiratory fitness (CRF) has been suggested to reduce the risk of metabolic syndrome (MetS). We aimed to longitudinally examine the changes of CRF on MetS and its risk factors from adolescence to adulthood. Methods and results: At the age of 15 years, 1076 subjects were recruited from 2 cohorts. CRF was measured on a cycle ergometer. MetS was classified as having at least 3 of the following parameters above the threshold of risk factors: waist circumference, triglycerides, high-density lipoprotein cholesterol (HDL), high blood pressure (BP) and fasting glucose. In addition, insulin, total cholesterol and low-density lipoprotein cholesterol were measured and homeostasis model assessment of insulin resistance (HOMA-IR) was calculated. Persistently high, increasing, decreasing and persistently low CRF groups were formed according to change in CRF from adolescence to adulthood. Longitudinal increase in CRF was positively associated with change in HDL and negatively associated with change in insulin, HOMA-IR, triglycerides, BP and prevalence of MetS after adjustment for potential confounders. Subjects with persistently low CRF had 11.5- to 34.4-times higher risk of MetS at the age of 25 and 33 years compared to subjects with persistently high CRF and 14.6- to 15.9-times higher risk compared to the increasing CRF group. Conclusion: Higher CRF is strongly related to lower values of MetS risk factors. Increasing CRF from adolescence to adulthood reduces the risk to have MetS later in adulthood. High CRF in adolescence that decreases during adulthood has similar risks to MetS compared to individuals with persistently low CRF. (C) 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:701 / 708
页数:8
相关论文
共 50 条
  • [41] Cardiorespiratory fitness and the metabolic syndrome: Roles of inflammation and abdominal obesity
    Wedell-Neergaard, Anne-Sophie
    Krogh-Madsen, Rikke
    Petersen, Gitte Lindved
    Hansen, Ase Marie
    Pedersen, Bente Klarlund
    Lund, Rikke
    Bruunsgaard, Helle
    PLOS ONE, 2018, 13 (03):
  • [42] Association of Leptin With Cardiorespiratory Fitness and Metabolic Syndrome in College Women
    Choi, Heagin
    Oh, Jung-il
    RESEARCH QUARTERLY FOR EXERCISE AND SPORT, 2010, 81 (01) : 14 - 15
  • [43] Associations between cardiorespiratory fitness and the metabolic syndrome in British men
    Ingle, Lee
    Mellis, Michelle
    Brodie, David
    Sandercock, Gavin R.
    HEART, 2017, 103 (07) : 516 - 520
  • [44] Prevalence of the metabolic syndrome across cardiorespiratory fitness levels in women
    Farrell, SW
    Cheng, YLJ
    Blair, SN
    OBESITY RESEARCH, 2004, 12 (05): : 824 - 830
  • [45] The joint association of serum vitamin D status and cardiorespiratory fitness with obesity and metabolic syndrome in Tehranian adults
    Farazi, Mena
    Jayedi, Ahmad
    Firouzabadi, Fatemeh Dehghani
    Noruzi, Zahra
    Moosavi, Hanieh
    Djafarian, Kurosh
    Shab-Bidar, Sakineh
    BRITISH JOURNAL OF NUTRITION, 2022, 128 (04) : 636 - 645
  • [46] Association between cardiorespiratory fitness and the prevalence of metabolic syndrome among Korean adults: a cross sectional study
    Hong, Sunghyun
    Lee, Junga
    Park, Jihye
    Lee, Mikyung
    Kim, Ji Young
    Kim, Kyong-Chol
    Kim, Sun Hyun
    Im, Jee Aee
    Chu, Sang Hui
    Suh, Sang Hoon
    Kim, Sang Hwan
    Jeon, Justin Y.
    BMC PUBLIC HEALTH, 2014, 14
  • [47] Effects of reducing sedentary behavior on cardiorespiratory fitness in adults with metabolic syndrome: A 6-month RCT
    Norha, Jooa
    Sjoros, Tanja
    Garthwaite, Taru
    Laine, Saara
    Saarenhovi, Maria
    Kallio, Petri
    Laitinen, Kirsi
    Houttu, Noora
    Vaha-Ypya, Henri
    Sievanen, Harri
    Loyttyniemi, Eliisa
    Vasankari, Tommi
    Knuuti, Juhani
    Kalliokoski, Kari K.
    Heinonen, Ilkka H. A.
    SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, 2023, 33 (08) : 1452 - 1461
  • [48] Association between cardiorespiratory fitness and the prevalence of metabolic syndrome among Korean adults: a cross sectional study
    Sunghyun Hong
    Junga Lee
    Jihye Park
    Mikyung Lee
    Ji Young Kim
    Kyong-Chol Kim
    Sun Hyun Kim
    Jee Aee Im
    Sang Hui Chu
    Sang Hoon Suh
    Sang Hwan Kim
    Justin Y Jeon
    BMC Public Health, 14
  • [49] Effects of aerobic interval training on metabolic complications and cardiorespiratory fitness in young adults with psychotic disorders: A pilot study
    Abdel-Baki, Amal
    Brazzini-Poisson, Veronique
    Marois, Francis
    Letendre, Elaine
    Karelis, Antony D.
    SCHIZOPHRENIA RESEARCH, 2013, 149 (1-3) : 112 - 115
  • [50] Association between cardiorespiratory fitness and metabolic health in overweight and obese adults
    Haapala, Eero A.
    Sjoros, Tanja
    Laine, Saara
    Garthwaite, Taru
    Kallio, Petri
    Saarenhovi, Maria
    Vaha-Ypya, Henri
    Loyttyniemi, Eliisa
    Sievanen, Harri
    Houttu, Noora
    Laitinen, Kirsi
    Kalliokoski, Kari
    Knuuti, Juhani
    Vasankari, Tommi
    Heinonen, Ilkka H.
    JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS, 2022, 62 (11): : 1526 - 1533