Changes in cardiorespiratory fitness through adolescence predict metabolic syndrome in young adults

被引:17
|
作者
Maestu, Evelin [1 ]
Harro, Jaanus [2 ]
Veidebaum, Toomas [3 ]
Kurrikoff, Triin [4 ]
Jurimae, Jaak [1 ]
Maestu, Jarek [1 ]
机构
[1] Univ Tartu, Fac Med, Inst Sport Sci & Physiotherapy, Dept Exercise Biol, Tartu, Estonia
[2] Univ Tartu, Fac Social Sci, Inst Psychol, Dept Neuropsychopharmacol, Tartu, Estonia
[3] Natl Inst Hlth Dev, Tallinn, Estonia
[4] Univ Tartu, Fac Social Sci, Inst Social Studies, Tartu, Estonia
关键词
Cardiorespiratory fitness; Cohort study; Metabolic syndrome risk factors; Metabolic health; Young adulthood; CARDIOVASCULAR RISK-FACTORS; ALL-CAUSE MORTALITY; PHYSICAL-ACTIVITY; CHILDHOOD; HEALTH; ADIPOSITY; CHILDREN; FATNESS; ASSOCIATIONS; OBESITY;
D O I
10.1016/j.numecd.2019.12.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and aims: Higher cardiorespiratory fitness (CRF) has been suggested to reduce the risk of metabolic syndrome (MetS). We aimed to longitudinally examine the changes of CRF on MetS and its risk factors from adolescence to adulthood. Methods and results: At the age of 15 years, 1076 subjects were recruited from 2 cohorts. CRF was measured on a cycle ergometer. MetS was classified as having at least 3 of the following parameters above the threshold of risk factors: waist circumference, triglycerides, high-density lipoprotein cholesterol (HDL), high blood pressure (BP) and fasting glucose. In addition, insulin, total cholesterol and low-density lipoprotein cholesterol were measured and homeostasis model assessment of insulin resistance (HOMA-IR) was calculated. Persistently high, increasing, decreasing and persistently low CRF groups were formed according to change in CRF from adolescence to adulthood. Longitudinal increase in CRF was positively associated with change in HDL and negatively associated with change in insulin, HOMA-IR, triglycerides, BP and prevalence of MetS after adjustment for potential confounders. Subjects with persistently low CRF had 11.5- to 34.4-times higher risk of MetS at the age of 25 and 33 years compared to subjects with persistently high CRF and 14.6- to 15.9-times higher risk compared to the increasing CRF group. Conclusion: Higher CRF is strongly related to lower values of MetS risk factors. Increasing CRF from adolescence to adulthood reduces the risk to have MetS later in adulthood. High CRF in adolescence that decreases during adulthood has similar risks to MetS compared to individuals with persistently low CRF. (C) 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:701 / 708
页数:8
相关论文
共 50 条
  • [21] Metabolic syndrome, obesity, and mortality - Impact of cardiorespiratory fitness
    Katzmarzyk, PT
    Ross, R
    Church, TS
    Blair, SN
    Janssen, I
    DIABETES CARE, 2005, 28 (02) : 391 - 397
  • [22] Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome
    Lakka, TA
    Laaksonen, DE
    Lakka, HM
    Männikkö, N
    Niskanen, LK
    Rauramaa, R
    Salonen, JT
    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2003, 35 (08): : 1279 - 1286
  • [23] Changes in Cardiorespiratory Fitness Predict Changes in Body Composition From Childhood to Adolescence: Findings From the European Youth Heart Study
    Ornelas, Rui T.
    Silva, Analiza M.
    Minderico, Claudia S.
    Sardinha, Luis B.
    PHYSICIAN AND SPORTSMEDICINE, 2011, 39 (02): : 78 - 86
  • [24] Physical activity, cardiorespiratory fitness, and metabolic syndrome in young Mexican and Mexican-American women
    Vella, Chantal A.
    Zubia, Raul Y.
    Ontiveros, Diana
    Cruz, Martha L.
    APPLIED PHYSIOLOGY NUTRITION AND METABOLISM-PHYSIOLOGIE APPLIQUEE NUTRITION ET METABOLISME, 2009, 34 (01): : 10 - 17
  • [25] Combined Impact of Cardiorespiratory Fitness and Visceral Adiposity on Metabolic Syndrome in Overweight and Obese Adults in Korea
    Kim, Sue
    Kim, Ji-Young
    Lee, Duk-Chul
    Lee, Hye-Sun
    Lee, Ji-Won
    Jeon, Justin Y.
    PLOS ONE, 2014, 9 (01):
  • [26] Self-reported and measured cardiorespiratory fitness similarly predict cardiovascular disease risk in young adults
    Ortega, F. B.
    Sanchez-Lopez, M.
    Solera-Martinez, M.
    Fernandez-Sanchez, A.
    Sjostrom, M.
    Martinez-Vizcaino, V.
    SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, 2013, 23 (06) : 749 - 757
  • [27] Daily Heart Rate in Relation to Cardiorespiratory Fitness and Metabolic Syndrome in HIV plus Hispanic Adults
    Medina-Encarnacion, Annette M.
    Romero-Reyes, Amarilys
    Ramirez-Marrero, Farah A.
    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2017, 49 (05): : 1016 - 1016
  • [28] Association between resting heart rate, metabolic syndrome and cardiorespiratory fitness in Korean male adults
    Kang, Seol-Jung
    Ha, Gi-Chul
    Ko, Kwang-Jun
    JOURNAL OF EXERCISE SCIENCE & FITNESS, 2017, 15 (01) : 27 - 31
  • [29] Cardiorespiratory Fitness and Metabolic Markers in Healthy Young Adult Men
    Yagura, Chiaki
    Takamura, Noboru
    Goto, Yoshinobu
    Sugihara, Hajime
    Sota, Takeshi
    Oka, Shinichiro
    Shimoda, Takeyoshi
    Yoshizumi, Kohei
    JOURNAL OF PHYSICAL THERAPY SCIENCE, 2011, 23 (06) : 845 - 849
  • [30] Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome
    Laaksonen, DE
    Lakka, HM
    Salonen, JT
    Niskanen, LK
    Rauramaa, R
    Lakka, TA
    DIABETES CARE, 2002, 25 (09) : 1612 - 1618