Vitamin D Deficiency Before Bariatric Surgery: Should Supplement Intake Be Routinely Prescribed?

被引:46
作者
Ducloux, Roxane [1 ,3 ]
Nobecourt, Estelle [1 ]
Chevallier, Jean-Marc [2 ]
Ducloux, Herve
Elian, Negib [1 ]
Altman, Jean-Jacques [1 ]
机构
[1] Hop Europeen Georges Pompidou, Serv Diabetol Endocrinol Nutr, Paris, France
[2] Hop Europeen Georges Pompidou, Serv Chirurg Digest, Paris, France
[3] Univ Paris 05, Fac Med, Paris, France
关键词
Vitamin D deficiency; Bariatric surgery; Morbid obesity; Systematic nutritional complementation; D INSUFFICIENCY; PREVENTION; PREVALENCE;
D O I
10.1007/s11695-010-0352-3
中图分类号
R61 [外科手术学];
学科分类号
摘要
Before bariatric surgery, we demonstrate a 96% rate of vitamin D deficiency in morbidly obese French patients: should supplement intake be routinely prescribed? We conducted a prospective observational study to demonstrate the prevalence of vitamin D deficiency in morbidly obese patients awaiting bariatric surgery. Clinical and biological data were collected on 50 successive patients. Data showed vitamin D deficiency in 96% (25-OH vitamin D = 31 +/- 13 nmol/l), with a cut-point of 50 nmol/l. Secondary hyperparathyroidism was found in 44% of patients with hypovitaminosis D (parathyroid hormone (PTH), 59 +/- 24 pg/ml). Impaired PTH level concerned 89% of this group, considering the cut-point at 30 pg/ml. No significant correlation appeared between vitamin D and calcium or phosphate levels. Before surgery, we demonstrated a higher incidence of vitamin D deficiency in morbidly obese French patients as compared to the general population. The incidence was also higher than previous American studies. Screening for hypovitaminosis D may routinely be considered in morbid obesity. Long-term observation is, however, needed to assess the advantages and potential side effects of systematic vitamin D supplements.
引用
收藏
页码:556 / 560
页数:5
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