Acylated oleanane-type triterpene oligoglycosides from the flower buds of Camellia sinensis var. assamica

被引：16

作者：

Ohta, Tomoe ^{[1
]}

Nakamura, Seikou ^{[1
]}

Nakashima, Souichi ^{[1
]}

Matsumoto, Takahiro ^{[1
]}

Ogawa, Keiko ^{[1
]}

Fujimoto, Katsuyoshi ^{[1
]}

Fukaya, Masashi ^{[1
]}

Yoshikawa, Masayuki ^{[1
]}

Matsuda, Hisashi ^{[1
]}

机构：

[1] Kyoto Pharmaceut Univ, Yamashina Ku, Kyoto 6078412, Japan

来源：

TETRAHEDRON | 2015年 / 71卷 / 05期

基金：

日本学术振兴会;

关键词：

Camellia sinensis var. assamica; Theaceae; Acylated oleanane-type triterpene; Floraassamsaponin; PRUNUS-MUME; ANTIALLERGIC ACTIVITY; ALDOSE REDUCTASE; MELANOGENESIS; CONSTITUENTS; SUCROSES; GLYCOSIDES; SAPOGENOL; SAPONIN; LEAVES;

D O I：

10.1016/j.tet.2014.12.049

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Eight new acylated oleanane-type triterpene oligoglycosides, floraassamsaponins I, II, III, IV, V, VI, VII, and VIII, were isolated from the flower buds of Camellia sinensis var. assamica. The chemical structures of new constituents were characterized on the basis of chemical and physicochemical evidence. In the present study, floraassamsaponins I and II with sugar moiety at 28-position were obtained from the flower buds of C. sinensis var. assamica. In the past, acylated triterpene oligoglycosides with sugar moiety at 28-position have not been isolated from the flower buds of Camellia sinensis var. sinensis. This finding is interesting from the perspective of chemotaxonomy of Camellia plants. In addition, acylated oleanane-type triterpene saponins significantly inhibited the aggregation of A beta 42. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：846 / 851

页数：6

共 18 条

[1] Structures of acylated sucroses from the flower buds of Prunus mume [J].

Fujimoto, Katsuyoshi ;

Nakamura, Seikou ;

Matsumoto, Takahiro ;

Ohta, Tomoe ;

Yoshikawa, Masayuki ;

Ogawa, Keiko ;

Kashiwazaki, Eri ;

Matsuda, Hisashi .

JOURNAL OF NATURAL MEDICINES, 2014, 68 (03) :481-487

[2] Hydrangeamines A and B, novel polyketide-type pseudoalkaloid-coupled secoiridoid glycosides from the flowers of Hydrangea macrophylla var. thunbergii [J].

Liu, Jiang ;

Nakamura, Seikou ;

Matsuda, Hisashi ;

Yoshikawa, Masayuki .

TETRAHEDRON LETTERS, 2013, 54 (01) :32-34

[3] Structure of diarylheptanoids with antiallergic activity from the rhizomes of Curcuma comosa [J].

Matsumoto, Takahiro ;

Nakamura, Seikou ;

Fujimoto, Katsuyoshi ;

Ohta, Tomoe ;

Ogawa, Keiko ;

Yoshikawa, Masayuki ;

Onishi, Eri ;

Fukaya, Masashi ;

Matsuda, Hisashi .

JOURNAL OF NATURAL MEDICINES, 2015, 69 (01) :142-147

[4] A Rare Glutamine Derivative from the Flower Buds of Daylily [J].

Matsumoto, Takahiro ;

Nakamura, Seikou ;

Ohta, Tomoe ;

Fujimoto, Katsuyoshi ;

Yoshikawa, Masayuki ;

Ogawa, Keiko ;

Matsuda, Hisashi .

ORGANIC LETTERS, 2014, 16 (11) :3076-3078

[5] Lignan Dicarboxylates and Terpenoids from the Flower Buds of Cananga odorata and Their Inhibitory Effects on Melanogenesis [J].

Matsumoto, Takahiro ;

Nakamura, Seikou ;

Nakashima, Souichi ;

Fujimoto, Katsuyoshi ;

Yoshikawa, Masayuki ;

Ohta, Tomoe ;

Ogawa, Keiko ;

Matsuda, Hisashi .

JOURNAL OF NATURAL PRODUCTS, 2014, 77 (04) :990-999

[6] Protective effects of caffeoylquinic acids on the aggregation and neurotoxicity of the 42-residue amyloid β-protein [J].

Miyamae, Yusaku ;

Kurisu, Manami ;

Murakami, Kazuma ;

Han, Junkyu ;

Isoda, Hiroko ;

Irie, Kazuhiro ;

Shigemori, Hideyuki .

BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 20 (19) :5844-5849

[7] Structures of acylated sucroses and an acylated flavonol glycoside and inhibitory effects of constituents on aldose reductase from the flower buds of Prunus mume [J].

Nakamura, Seikou ;

Fujimoto, Katsuyoshi ;

Matsumoto, Takahiro ;

Ohta, Tomoe ;

Ogawa, Keiko ;

Tamura, Haruka ;

Matsuda, Hisashi ;

Yoshikawa, Masayuki .

JOURNAL OF NATURAL MEDICINES, 2013, 67 (04) :799-806

[8] Acylated sucroses and acylated quinic acids analogs from the flower buds of Prunus mume and their inhibitory effect on melanogenesis [J].

Nakamura, Seikou ;

Fujimoto, Katsuyoshi ;

Matsumoto, Takahiro ;

Nakashima, Souichi ;

Ohta, Tomoe ;

Ogawa, Keiko ;

Matsuda, Hisashi ;

Yoshikawa, Masayuki .

PHYTOCHEMISTRY, 2013, 92 :128-136

[9] Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells [J].

Nakamura, Seikou ;

Nakashima, Souichi ;

Tanabe, Genzo ;

Oda, Yoshimi ;

Yokota, Nami ;

Fujimoto, Katsuyoshi ;

Matsumoto, Takahiro ;

Sakuma, Rika ;

Ohta, Tomoe ;

Ogawa, Keiko ;

Nishida, Shino ;

Miki, Hisako ;

Matsuda, Hisashi ;

Muraoka, Osamu ;

Yoshikawa, Masayuki .

BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 21 (03) :779-787

[10] Melanogenesis Inhibitory and Fibroblast Proliferation Accelerating Effects of Noroleanane- and Oleanane-Type Triterpene Oligoglycosides from the Flower Buds of Camellia japonica [J].

Nakamura, Seikou ;

Moriura, Toshitsugu ;

Park, Sunmi ;

Fujimoto, Katsuyoshi ;

Matsumoto, Takahiro ;

Ohta, Tomoe ;

Matsuda, Hisashi ;

Yoshikawa, Masayuki .

JOURNAL OF NATURAL PRODUCTS, 2012, 75 (08) :1425-1430

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