New chondropsin macrolide lactams from marine sponges in the genus Ircinia

被引:25
作者
Rashid, MA
Gustafson, KR
Boyd, MR
机构
[1] NCI, Div Basic Sci, Lab Drug Discovery Res & Dev, Frederick, MD 21702 USA
[2] SAIC Frederick, Frederick, MD 21702 USA
基金
美国国家卫生研究院;
关键词
macrolide lactams; polyketide; chondropsins; Ircinia ramosa;
D O I
10.1016/S0040-4039(00)02348-0
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Two new polyketide-derived macrolide lactams, identified as 73-deoxychondropsin A (2) and chondropsin C (3), have been isolated from two different collections of marine sponges which belong to the genus 6 Ircinia. An Australian collection of Ircinia ramosa provided 73-deoxychondropsin A (2), while samples of Ircinia sp. collected in the Philippines yielded chondropsin C (3). The structures of 2 and 3 were assigned by interpretation of their spectral data. Published by Elsevier Science Ltd.
引用
收藏
页码:1623 / 1626
页数:4
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