Low Levels of Energy Expenditure in Childhood Cancer Survivors: Implications for Obesity Prevention

被引:16
作者
Zhang, Fang Fang [1 ,2 ]
Roberts, Susan B. [3 ]
Parsons, Susan K. [4 ,6 ,7 ]
Must, Aviva [8 ]
Kelly, Michael J. [5 ,7 ]
Wong, William W. [9 ]
Saltzman, Edward [3 ]
机构
[1] Tufts Univ, Friedman Sch Nutr Sci & Policy, Dept Nutr Sci, Boston, MA 02111 USA
[2] Tufts Univ, Nutr Epidemiol Program, Boston, MA 02111 USA
[3] Tufts Univ, Jean Mayer USDA Human Nutr Res Ctr Aging, Energy Metab Lab, Boston, MA 02111 USA
[4] Tufts Med Ctr, Inst Clin Res & Hlth Policy Studies, Boston, MA USA
[5] Tufts Med Ctr, Floating Hosp Children, Div Pediat Hematol Oncol, Boston, MA USA
[6] Tufts Univ, Sch Med, Dept Med, Boston, MA 02111 USA
[7] Tufts Univ, Sch Med, Dept Pediat, Boston, MA 02111 USA
[8] Tufts Univ, Sch Med, Dept Publ Hlth & Community Med, Boston, MA 02111 USA
[9] ARS, Baylor Coll Med, USDA, Childrens Nutr Res Ctr, Houston, TX USA
基金
美国国家卫生研究院;
关键词
total energy expenditure; childhood cancer survivors; obesity; DOUBLY-LABELED WATER; ACUTE LYMPHOBLASTIC-LEUKEMIA; NUTRITIONAL-STATUS; PHYSICAL-ACTIVITY; ADULT SURVIVORS; METABOLIC-RATE; MULTIPLE-PASS; CHILDREN; OVERWEIGHT; VALIDATION;
D O I
10.1097/MPH.0000000000000250
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Childhood cancer survivors are at an increased risk of obesity but causes for this elevated risk are uncertain. We evaluated total energy expenditure in childhood cancer survivors using the doubly labeled water method in a cross-sectional study of 17 survivors of pediatric leukemia or lymphoma (median age, 11.5 y). Mean total energy expenditure was 2073 kcal/d, which was nearly 500 kcal/d lower than estimated energy requirements with recommended levels of physical activity. This energy gap is likely to contribute to the risk of obesity in this population and future trials are needed to assess implications and potential treatment strategies.
引用
收藏
页码:232 / 236
页数:5
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