Helix change of polypeptides in the solid state as studied by NMR spectroscopy

被引：6
作者：
Ando, I
机构：
[1] Department of Polymer Chemistry, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo
来源：
MACROMOLECULAR SYMPOSIA | 1996年 / 101卷
关键词：
D O I：
10.1002/masy.19961010142
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The conformational characterization of solid polypeptides has been carried out by means of high-resolution solid-state NMR. It has been demonstrated that high-resolution solid-state NMR spectroscopy is a very useful means for elucidating the structure of polypeptides and proteins in the solid state.
引用
收藏
页码：371 / 377
页数：7
相关论文
共 14 条
[1]   CONFORMATIONAL BEHAVIOR OF POLY(BETA-BENZYL L-ASPARTATE) IN THE SOLID-STATE AS STUDIED BY VARIABLE-TEMPERATURE C-13 CROSS-POLARIZATION MAGIC ANGLE SPINNING NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY [J].
AKIEDA, T ;
MIMURA, H ;
KUROKI, S ;
KUROSU, H ;
ANDO, I .
MACROMOLECULES, 1992, 25 (21) :5794-5797
[2]   PRIMARY AND SECONDARY STRUCTURES OF SYNTHETIC-POLYMER SYSTEMS AS STUDIED BY C-13 NMR-SPECTROSCOPY [J].
ANDO, I ;
YAMANOBE, T ;
ASAKURA, T .
PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, 1990, 22 :349-400
[3]   CONFORMATION-DEPENDENT C-13 NMR CHEMICAL-SHIFTS OF POLY(L-ALANINE) IN THE SOLID-STATE - FPT INDO CALCULATION OF N-ACETYL-N'-METHYL-L-ALANINE AMIDE AS A MODEL-COMPOUND OF POLY(L-ALANINE) [J].
ANDO, I ;
SAITO, H ;
TABETA, R ;
SHOJI, A ;
OZAKI, T .
MACROMOLECULES, 1984, 17 (03) :457-461
[4]   STRUCTURAL STUDY OF PEPTIDES CONTAINING L-ALANINE RESIDUES BY AB-INITIO CHEMICAL SHIELDING CALCULATION [J].
ASAKAWA, N ;
KUROSU, H ;
ANDO, I .
JOURNAL OF MOLECULAR STRUCTURE, 1994, 323 :279-285
[5]  
Kurosu H., 1994, ANNU REP NMR SPECTRO, V28, P189
[6]   CONFORMATIONAL BEHAVIOR OF POLY (BETA-ASPARTATE) WITH N-ALKYL SIDE-CHAINS IN THE SOLID-STATE AS STUDIED BY C-13-CP/MAS-NMR SPECTROSCOPY [J].
OKABE, M ;
YAMANOBE, T ;
KOMOTO, T ;
WATANABE, J ;
ANDO, I ;
UEMATSU, I .
JOURNAL OF MOLECULAR STRUCTURE, 1989, 213 :213-220
[7]   CONFORMATIONAL CHARACTERIZATION OF POLYPEPTIDES IN THE SOLID-STATE AS VIEWED FROM THE CONFORMATION-DEPENDENT C-13 CHEMICAL-SHIFTS DETERMINED BY THE C-13 CROSS POLARIZATION MAGIC ANGLE SPINNING METHOD - OLIGO(L-ALANINE), POLY(L-ALANINE), CO-POLYMERS OF L-ALANINE AND D-ALANINE, AND CO-POLYMERS OF L-ALANINE WITH N-METHYL-L-ALANINE OR N-BENZYL-L-ALANINEGL [J].
SAITO, H ;
TABETA, R ;
SHOJI, A ;
OZAKI, T ;
ANDO, I .
MACROMOLECULES, 1983, 16 (07) :1050-1057
[8]   A HIGH-RESOLUTION C-13 NMR-STUDY OF SOLID POLY(BETA-BENZYL-L-ASPARTATE) BY THE CROSS POLARIZATION-MAGIC ANGLE SPINNING METHOD - DISTINCTION OF THE RIGHT-HANDED ALPHA-HELIX, LEFT-HANDED ALPHA-HELIX, OMEGA-HELIX, AND BETA-SHEET FORMS BY CONFORMATION-DEPENDENT C-13 CHEMICAL-SHIFTS [J].
SAITO, H ;
TABETA, R ;
ANDO, I ;
OZAKI, T ;
SHOJI, A .
CHEMISTRY LETTERS, 1983, (09) :1437-1440
[9]  
SAITO H, 1989, ANN REPORT NMR SPECT, V26, P55
[10]  
SAITO H, 1985, MAGNETIC RESONANCE B, P195
12