The Aryne Ene Reaction

被引：6
作者：
Yang, Yun [1 ]
Jones, Christopher R. [1 ]
机构：
[1] Queen Mary Univ London, Sch Phys & Chem Sci, Mile End Rd, London E1 4NS, England
来源：
SYNTHESIS-STUTTGART | 2022年 / 54卷 / 22期
基金：
英国工程与自然科学研究理事会;
关键词：
aryne; ene reaction; arylation; arene functionalization; DIELS-ALDER; BENZYNE; ARYLATION; STEREOCHEMISTRY; MECHANISM; ADDUCTS; OLEFINS;
D O I：
10.1055/a-1827-2987
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Intermolecular aryne ene reactions present opportunities to arylate a wide range of unsaturated substrates in a single step, whilst intramolecular reactions provide expedient access to valuable benzo-fused carbo- and heterocyclic frameworks. This short review will chart the development of the aryne ene reaction from initial reports that rationalise unexpected byproduct formation in competing [4+2] and [2+2] cycloadditions through to its exploitation in contemporary synthetic methodology.
引用
收藏
页码：5042 / 5054
页数：13
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