Chiral bis(N-sulfonylamino)phosphine- and TADDOL-phosphite-oxazoline ligands:: Synthesis and application in asymmetric catalysis

被引:100
作者
Hilgraf, R [1 ]
Pfaltz, A [1 ]
机构
[1] Univ Basel, Dept Chem, CH-4056 Basel, Switzerland
关键词
asymmetric allylic substitution; asymmetric catalysis; asymmetric hydrogenation; N; P ligands; oxazolines;
D O I
10.1002/adsc.200404168
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A series of N,P-ligands has been prepared, containing a chiral oxazoline ring and as a second chiral unit a bis(N-sulfonylamino)phosphine group embedded in a diazaphospholidine ring or a cyclic phosphite group derived from TADDOL. These modular ligands are readily synthesized from chiral amino alcohols and chiral 1,2-diamines or TADDOLs. Palladium and iridium complexes derived from these ligands were found to be efficient catalysts for enantioselective allylic alkylation and olefin hydrogenation, respectively.
引用
收藏
页码:61 / 77
页数:17
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