COVID-19 mRNA igi? ?1/4 f T z offI- igiιHof 201 Two Cases of Cataract after COVID-19 mRNA Vaccine Injection

被引:0
作者
Yoon, Eunyu [1 ]
Choi, Jaewon [1 ]
Ahn, Minwon [1 ]
Park, Minji [1 ,2 ]
机构
[1] Sungmo Eye Hosp, Busan, South Korea
[2] Sungmo Eye Hosp, 409 Haeun daero, Busan 48064, South Korea
来源
JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY | 2022年 / 63卷 / 12期
关键词
Cataract; COVID-19; vaccines; mRNA vaccine; SARS-CoV-2;
D O I
10.3341/jkos.2022.63.12.1033
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To report two cases of cataract that progressed after COVID-19 mRNA vaccination. Case summary: Two patients visited our clinic with decreased visual acuity in the left eye that began after mRNA vaccine. A 40-year-old man visited our hospital with decreased visual acuity in the left eye that developed 1 week after injection of the sec-ond dose of mRNA-1273 (Moderna (R),Cambridge, UK). A 40-year-old woman visited our clinic with decreased visual acuity in the left eye that occurred on day 46 after the injection of the third dose of BNT162b2 (Pfizer (R), New York, NY, USA). Neither case had any relevant ophthalmic history, and there was no clear optic neuropathy or retinopathy on fundus examination. After phacoe-mulsification and intraocular lens implantation, the best-corrected visual acuity improved, and intraocular pressure has remained stable. Conclusions: The possibility of cataract development or progression after COVID-19 mRNA vaccine injection should be considered.
引用
收藏
页码:1033 / 1037
页数:5
相关论文
共 13 条
[1]  
Alderson Jennifer, 2021, Oxf Open Immunol, V2, piqab010, DOI 10.1093/oxfimm/iqab010
[2]  
Berman E., 1991, BIOCH EYE
[3]   A comprehensive analysis of the efficacy and safety of COVID-19 vaccines [J].
Cai, Changjing ;
Peng, Yinghui ;
Shen, Edward ;
Huang, Qiaoqiao ;
Chen, Yihong ;
Liu, Ping ;
Guo, Cao ;
Feng, Ziyang ;
Gao, Le ;
Zhang, Xiangyang ;
Gao, Yan ;
Liu, Yihan ;
Han, Ying ;
Zeng, Shan ;
Shen, Hong .
MOLECULAR THERAPY, 2021, 29 (09) :2794-2805
[4]  
EMA European Medicines Agency., 2021, ASTRAZENECAS COVID 1
[5]   Anterior Uveitis and Cataract After Rubella Vaccination: A Case Report of a 12-Month-Old Girl [J].
Ferrini, Walter ;
Aubert, Vincent ;
Balmer, Aubin ;
Munier, Francis L. ;
Abouzeid, Hana .
PEDIATRICS, 2013, 132 (04) :E1035-E1038
[6]  
Korea Disease Control and Prevention Agency, 2021, Q0A SARS COV 2 VACC
[7]   The Eye of the Storm: COVID-19 Vaccination and the Eye [J].
Ng, Xin Le ;
Betzler, Bjorn Kaijun ;
Ng, Sean ;
Chee, Soon Phaik ;
Rajamani, Lakshminarayanan ;
Singhal, Amit ;
Rousselot, Andres ;
Pavesio, Carlos E. ;
Gupta, Vishali ;
de Smet, Marc D. ;
Agrawal, Rupesh .
OPHTHALMOLOGY AND THERAPY, 2022, 11 (01) :81-100
[8]   mRNA vaccines - a new era in vaccinology [J].
Pardi, Norbert ;
Hogan, Michael J. ;
Porter, Frederick W. ;
Weissman, Drew .
NATURE REVIEWS DRUG DISCOVERY, 2018, 17 (04) :261-279
[9]   SARS-CoV-2 candidate vaccines - composition, mechanisms of action and stages of clinical development [J].
Rodriguez-Coira, Juan ;
Sokolowska, Milena .
ALLERGY, 2021, 76 (06) :1922-1924
[10]   Intraocular cytokine profile and autoimmune reactions in retinitis pigmentosa, age-related macular degeneration, glaucoma and cataract [J].
ten Berge, Josianne C. ;
Fazil, Zainab ;
van den Born, Ingeborgh ;
Wolfs, Roger C. W. ;
Schreurs, Marco W. J. ;
Dik, Wim A. ;
Rothova, Aniki .
ACTA OPHTHALMOLOGICA, 2019, 97 (02) :185-192