Behavior of stem cells under outer-space microgravity and ground-based microgravity simulation

被引：31

作者：

Zhang, Cui ^{[1
]}

Li, Liang ^{[1
]}

Chen, Jianling ^{[1
]}

Wang, Jinfu ^{[1
]}

机构：

[1] Zhejiang Univ, Coll Life Sci, Inst Cell & Dev Biol, Hangzhou 310058, Zhejiang, Peoples R China

来源：

CELL BIOLOGY INTERNATIONAL | 2015年 / 39卷 / 06期

关键词：

development; differentiation; microgravity; stem cells; tissue engineering; MODELED MICROGRAVITY; BONE-MARROW; OSTEOGENIC DIFFERENTIATION; CULTURE SYSTEM; IN-VITRO; PROLIFERATION; ADIPOGENESIS; SPACEFLIGHT; BIOREACTOR; PHENOTYPE;

D O I：

10.1002/cbin.10452

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

With rapid development of space engineering, research on life sciences in space is being conducted extensively, especially cellular and molecular studies on space medicine. Stem cells, undifferentiated cells that can differentiate into specialized cells, are considered a key resource for regenerative medicine. Research on stem cells under conditions of microgravity during a space flight or a ground-based simulation has generated several excellent findings. To help readers understand the effects of outer space and ground-based simulation conditions on stem cells, we reviewed recent studies on the effects of microgravity (as an obvious environmental factor in space) on morphology, proliferation, migration, and differentiation of stem cells.

引用

页码：647 / 656

页数：10

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