Molecular Mechanism and Targets of the Antimicrobial Activity of Metal Nanoparticles

被引：1

作者：

Oktar, Faik N. ^{[1
,2
]}

Yetmez, Mehmet ^{[3
]}

Ficai, Denisa ^{[4
]}

Ficai, Anton ^{[4
]}

Dumitru, Florica ^{[5
]}

Pica, Alexandra ^{[4
]}

机构：

[1] Marmara Univ, Fac Engn, Dept Bioengn, Istanbul, Turkey

[2] Marmara Univ, Nanotechnol Biomat Applicat & Res Ctr, Istanbul, Turkey

[3] Bulent Ecevit Univ, Fac Engn, Dept Mech Engn, Zonguldak, Turkey

[4] Univ Politehn Bucuresti, Ctr Micro & Nanotechnol, Bucharest 011061, Romania

[5] Res Inst Adv Coatings, Bucharest, Romania

来源：

CURRENT TOPICS IN MEDICINAL CHEMISTRY | 2015年 / 15卷 / 16期

关键词：

Antibacterial; Antiviral; Drug-multiresistant bacteria; Molecular mechanism; SILVER NANOPARTICLES; ANTIBACTERIAL ACTIVITY; ESCHERICHIA-COLI; GOLD NANOPARTICLES; MEDIATED TOXICITY; MGO NANOPARTICLES; DOPED TIO2; ZNO; COPPER; NANOMATERIALS;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The emergence of multi-resistant bacteria to drugs is recognized as a major cause of the increasing number of deaths in hospitals. Killing these bacteria require multiple expensive drugs that can have side effects. Metal nanoparticles may provide a new strategy to combat them. Due the antimicrobial and antiviral properties, nanoparticles (NPs) have outstanding biological properties that can be handled properly for desired applications. This review presents antibacterial and antiviral activity of metal NPs, including the molecular mechanisms by which NPs annihilate multidrug-resistant bacteria.

引用

页码：1583 / 1588

页数：6

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