Non-invasive Observation of Human Tissue Samples with Full Field Optical Coherence Tomography

被引：2
作者：
Mu, Ning [1 ]
Gao, Wanrong [1 ]
Zhou, Yawen [1 ]
机构：
[1] Nanjing Univ Sci & Technol, Dept Opt Engn, Nanjing 210094, Peoples R China
来源：
CHINESE JOURNAL OF ELECTRONICS | 2019年 / 28卷 / 05期
基金：
中国国家自然科学基金;
关键词：
biological tissues; biomedical optical imaging; cancer; liver; medical image processing; optical tomography; fresh human samples; tissue microstructures; normal tissue; cancerous tissue; tissue surface; depth-resolved images; face images; noninvasive observation; human tissue samples; Full field optical coherence tomography; human esophagus; uterus samples; ln imaging process; En face images; Optical sectioning imaging; Full field optical coherence tomography (FFOCT); Tissue microstructures; CLASSIFICATION; MICROSCOPY; MODEL;
D O I：
10.1049/cje.2019.06.018
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
In this work, we report on non-invasive observation of human esophagus, liver, and uterus samples with Full field optical coherence tomography (FFOCT). ln imaging process, fresh human samples were fixed in formalin immediately after excision and then imaged directly without staining and cutting the samples into a serial of thin slices. Tissue microstructures of each type of normal or cancerous tissue as well as their changes with the increase of the depth beneath tissue surface can be identified in the depth-resolved images. The results demonstrate the potential of applications of the en face images in clinic practice.
引用
收藏
页码：987 / 992
页数：6
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