Glucocorticoids in pediatric inflammatory bowel disease

被引：18
|
作者：
Sidoroff, Marianne [1 ]
Kolho, Kaija-Leena
机构：
[1] Univ Helsinki, Childrens Hosp, Helsinki 00029, Finland
来源：
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 2012年 / 47卷 / 07期
关键词：
children; Crohn's disease; steroid; ulcerative colitis; BONE-MINERAL DENSITY; ULCERATIVE-COLITIS; CROHNS-DISEASE; CORTICOSTEROID-THERAPY; MONONUCLEAR-CELLS; ORAL PREDNISOLONE; BCLI POLYMORPHISM; STEROID TREATMENT; NATURAL-HISTORY; MESSENGER-RNA;
D O I：
10.3109/00365521.2012.679681
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Children with moderate to severe inflammatory bowel disease (IBD) are treated with systemic glucocorticoids (GCs). The majority of the patients respond to the given treatment; however, steroid resistance and dependency are significant clinical problems. Also therapy-related side effects limit the use of GCs in the control of active inflammation. This review summarizes recent knowledge of GC treatment in pediatric patients with IBD.
引用
收藏
页码：745 / 750
页数：6
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