Biodegradable Ceramics Consisting of Hydroxyapatite for Orthopaedic Implants
被引:15
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作者:
Monsees, Thomas K.
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Univ Western Cape, Dept Med Biosci, ZA-7535 Bellville, South AfricaUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Monsees, Thomas K.
[1
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Azem, Funda Ak
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机构:
Dokuz Eylul Univ, Engn Fac, Met & Mat Engn Dept, Tinaztepe Campus, TR-35397 Izmir, TurkeyUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Azem, Funda Ak
[2
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Cotrut, Cosmin Mihai
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机构:
Univ Politehn Bucuresti, Fac Mat Sci & Engn, 313 Spl Independentei, Bucharest 060042, Romania
Natl Res Tomsk Polytech Univ, Dept Expt Phys, Lenin Ave 43, Tomsk 634050, RussiaUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Cotrut, Cosmin Mihai
[3
,4
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Braic, Mariana
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机构:
Natl Inst Optoelect, 409 Atomistilor St, Magurele 77125, RomaniaUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Braic, Mariana
[5
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Abdulgader, Radwan
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机构:
Univ Western Cape, Dept Med Biosci, ZA-7535 Bellville, South AfricaUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Abdulgader, Radwan
[1
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Pana, Iulian
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机构:
Natl Inst Optoelect, 409 Atomistilor St, Magurele 77125, RomaniaUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Pana, Iulian
[5
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Birlik, Isil
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机构:
Dokuz Eylul Univ, Engn Fac, Met & Mat Engn Dept, Tinaztepe Campus, TR-35397 Izmir, TurkeyUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Birlik, Isil
[2
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Kiss, Adrian
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h-index: 0
机构:
Natl Inst Optoelect, 409 Atomistilor St, Magurele 77125, RomaniaUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Kiss, Adrian
[5
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Booysen, Robin
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机构:
Univ Western Cape, Dept Med Biosci, ZA-7535 Bellville, South AfricaUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Booysen, Robin
[1
]
Vladescu, Alina
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机构:
Natl Res Tomsk Polytech Univ, Dept Expt Phys, Lenin Ave 43, Tomsk 634050, Russia
Natl Inst Optoelect, 409 Atomistilor St, Magurele 77125, RomaniaUniv Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
Vladescu, Alina
[4
,5
]
机构:
[1] Univ Western Cape, Dept Med Biosci, ZA-7535 Bellville, South Africa
[2] Dokuz Eylul Univ, Engn Fac, Met & Mat Engn Dept, Tinaztepe Campus, TR-35397 Izmir, Turkey
[3] Univ Politehn Bucuresti, Fac Mat Sci & Engn, 313 Spl Independentei, Bucharest 060042, Romania
[4] Natl Res Tomsk Polytech Univ, Dept Expt Phys, Lenin Ave 43, Tomsk 634050, Russia
[5] Natl Inst Optoelect, 409 Atomistilor St, Magurele 77125, Romania
This study aims to analyze hydroxyapatite (HAP) coatings enriched with Mg and Ti prepared by a magnetron sputtering technique on Ti6Al4V substrate. For preparation of the coatings, three magnetron targets (HAP, MgO and TiO2) were simultaneously co-worked. The concentration of Mg added was varied by modifying the power applied to the MgO target. In all coatings, the Ti concentration was maintained constant by keeping the same cathode power fed during the whole deposition. The influence of different Mg dopant contents on the formation of phase, microstructure and morphology of the obtained Ti-doped HAP coatings were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). Moreover, the effects of Mg addition upon corrosion, mechanical and biological properties were also investigated. Mg- and Ti-doped HAP coating obtained at low radio-frequency (RF) power fed to the MgO target provided material with high corrosion resistance compared to other coatings and bare alloy. A slight decrease in hardness of the coatings was found after the Mg addition, from 8.8 to 5.7 GPa. Also, the values of elastic modulus were decreased from 87 to 53 GPa, this being an advantage for biomedical applications. The coatings with low Mg concentration proved to have good deformation to yielding and higher plastic properties. Biological test results showed that the novel surfaces exhibited excellent properties for the adhesion and growth of bone cells. Moreover, early adherent vital cell numbers were significantly higher on both coatings compared to Ti6Al4V, suggesting that Mg ions may accelerate initial osteoblast adhesion and proliferation.
机构:
Fujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R ChinaFujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R China
Li, Xiaopei
Lin, Erli
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机构:
Fujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R China
Nagoya Inst Technol, Dept Phys Sci & Engn, Nagoya, Aichi 4668555, JapanFujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R China
Lin, Erli
Wang, Kaixuan
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机构:
Fujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R ChinaFujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R China
Wang, Kaixuan
Ke, Rongguo
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机构:
Fujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R ChinaFujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R China
Ke, Rongguo
Kure-Chu, Song-Zhu
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机构:
Nagoya Inst Technol, Dept Phys Sci & Engn, Nagoya, Aichi 4668555, JapanFujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R China
Kure-Chu, Song-Zhu
Xiao, Xiufeng
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Fujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R ChinaFujian Normal Univ, Coll Chem & Mat Sci, Fujian Prov Key Lab Adv Mat Oriented Chem Engn, Fuzhou 350007, Peoples R China
机构:
Univ Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R ChinaUniv Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China
Wong, Hoi Man
Yeung, Kelvin W. K.
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Univ Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R ChinaUniv Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China
Yeung, Kelvin W. K.
Lam, Kin On
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机构:
Univ Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R ChinaUniv Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China
Lam, Kin On
Tam, Vivian
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机构:
Univ Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R ChinaUniv Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China
Tam, Vivian
Chu, Paul K.
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机构:
City Univ Hong Kong, Dept Phys & Mat Sci, Kowloon, Hong Kong, Peoples R ChinaUniv Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China
Chu, Paul K.
Luk, Keith D. K.
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机构:
Univ Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R ChinaUniv Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China
Luk, Keith D. K.
Cheung, Kenneth M. C.
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机构:
Univ Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R ChinaUniv Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China
机构:
Ctr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, HungaryCtr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, Hungary
Furko, Monika
Horvath, Zsolt E.
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Ctr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, HungaryCtr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, Hungary
Horvath, Zsolt E.
Sulyok, Attila
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Ctr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, HungaryCtr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, Hungary
Sulyok, Attila
Kis, Viktoria K.
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机构:
Ctr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, HungaryCtr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, Hungary
Kis, Viktoria K.
Balazsi, Katalin
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机构:
Ctr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, HungaryCtr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, Hungary
Balazsi, Katalin
Mihaly, Judith
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机构:
Res Ctr Nat Sci, Inst Mat & Environm Chem, Magyar Tudosok Korutja 2, H-1117 Budapest, HungaryCtr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, Hungary
Mihaly, Judith
Balazsi, Csaba
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机构:
Ctr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, HungaryCtr Energy Res, Inst Tech Phys & Mat Sci, Konkoly Thege Str 29-33, H-1121 Budapest, Hungary
机构:
Univ Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, MalaysiaUniv Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, Malaysia
Bakhsheshi-Rad, H. R.
Hamzah, E.
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Univ Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, MalaysiaUniv Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, Malaysia
Hamzah, E.
Ismail, A. F.
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Univ Teknol Malaysia, Adv Membrane Technol Res Ctr AMTEC, Johor Baharu 81310, Johor, MalaysiaUniv Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, Malaysia
Ismail, A. F.
Sharer, Z.
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机构:
Univ Teknol Malaysia, Inst Oil & Gas, UTM MPRC, Johor Baharu 81310, Johor, MalaysiaUniv Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, Malaysia
Sharer, Z.
Abdul-Kadir, M. R.
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Univ Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, MalaysiaUniv Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, Malaysia
Abdul-Kadir, M. R.
Daroonparvar, M.
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Univ Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, MalaysiaUniv Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, Malaysia
Daroonparvar, M.
Saud, Safaa N.
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Univ Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, MalaysiaUniv Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, Malaysia