Management of inflammatory bowel disease in the pregnant patient

被引:23
作者
Habal, Flavio M. [1 ]
Ravindran, Nikila C. [2 ]
机构
[1] Univ Hlth Network, Toronto Gen Hosp, Dept Med, Div Gastroenterol, Toronto, ON M5G 2C4, Canada
[2] Univ Toronto, Fac Med, Toronto, ON, Canada
关键词
inflammatory bowel disease; ulcerative colitis; Crohn's disease; fertility; pregnancy; breastfeeding;
D O I
10.3748/wjg.14.1326
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Inflammatory bowel disease (IBD) is a chronic disorder affecting young adults in their reproductive years. Many young women with IBD express concern about the effect their disease will have on fertility, pregnancy course and fetal development. This article presents an approach to management of IBD in the pregnant patient, including counseling and investigation, and summarizes existing data on the safety of medications used to treat IBD in pregnancy and breastfeeding. (c) 2008 WJG. All rights reserved.
引用
收藏
页码:1326 / 1332
页数:7
相关论文
共 66 条
[1]   SAFETY OF AZATHIOPRINE IN PREGNANCY IN INFLAMMATORY BOWEL-DISEASE [J].
ALSTEAD, EM ;
RITCHIE, JK ;
LENNARDJONES, JE ;
FARTHING, MJG ;
CLARK, ML .
GASTROENTEROLOGY, 1990, 99 (02) :443-446
[2]   Inflammatory bowel disease in pregnancy [J].
Alstead, EM ;
Nelson-Piercy, C .
GUT, 2003, 52 (02) :159-161
[3]   Inflammatory bowel disease in pregnancy [J].
Alstead, EM .
POSTGRADUATE MEDICAL JOURNAL, 2002, 78 (915) :23-26
[4]   INCREASED RISK OF PRETERM BIRTH FOR WOMEN WITH INFLAMMATORY BOWEL-DISEASE [J].
BAIRD, DD ;
NARENDRANATHAN, M ;
SANDLER, RS .
GASTROENTEROLOGY, 1990, 99 (04) :987-994
[5]   Uneventful pregnancy and neonatal outcome with tacrolimus in refractory ulcerative colitis [J].
Baumgart, DC ;
Sturm, A ;
Wiedenmann, B ;
Dignass, AU .
GUT, 2005, 54 (12) :1822-1823
[6]  
BERKOVITCH M, 1994, OBSTET GYNECOL, V84, P535
[7]   First-trimester exposure to amoxycillin/clavulanic acid: a prospective, controlled study [J].
Berkovitch, M ;
Diav-Citrin, O ;
Greenberg, R ;
Cohen, M ;
Bulkowstein, M ;
Shechtman, S ;
Bortnik, O ;
Arnon, J ;
Ornoy, A .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2004, 58 (03) :298-302
[8]   Effects of immunosuppressive drugs during pregnancy [J].
Bermas, BL ;
Hill, JA .
ARTHRITIS AND RHEUMATISM, 1995, 38 (12) :1722-1732
[9]   INVITRO METABOLISM OF PREDNISOLONE, DEXAMETHASONE, BETAMETHASONE, AND CORTISOL BY HUMAN PLACENTA [J].
BLANFORD, AT ;
MURPHY, BEP .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1977, 127 (03) :264-267
[10]  
BOULTON R, 1994, AM J GASTROENTEROL, V89, P931