Unrelated bone marrow transplantation as a rescue procedure following inadvertent loss of an autologous bone marrow graft

被引：0

作者：

Oudshoorn, M

Falkenburg, JHF

Ebeling, LJ

Haak, HL

Wijermans, PW

Fibbe, WE

Willemze, R

vanRood, JJ

机构：

[1] UNIV LEIDEN HOSP,DEPT IMMUNOHAEMATOL,NL-2300 RC LEIDEN,NETHERLANDS

[2] UNIV LEIDEN HOSP,BLOOD BANK,NL-2300 RC LEIDEN,NETHERLANDS

[3] LEIDEN UNIV HOSP,DEPT HAEMATOL,LEIDEN,NETHERLANDS

[4] LEIJENBURG HOSP,DEPT HAEMATOL,THE HAGUE,NETHERLANDS

来源：

BONE MARROW TRANSPLANTATION | 1996年 / 18卷 / 02期

关键词：

MUD search; BMT; rescue search;

D O I：

暂无

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We report a 27-year-old male patient with acute myeloid leukaemia who was successfully treated with an unrelated bone marrow graft within 7 days following the loss of his autologous bone marrow graft. Several factors were found to be essential in order to locate an HLA-ABDR (DRB1)DQ(DQB1) identical, sex-matched, CMV-negative and ABO compatible donor within a week, These included a common HLA phenotype of the patient, the presence of an experienced donor registry in close proximity to a blood bank associated with an HLA laboratory, a large donor file with fully HLA-ABDR typed donors and the almost exclusive use of blood bank donors as potential bone marrow donors, The possibility of further streamlining the logistics of finding a suitable unrelated bone marrow donor is discussed.

引用

页码：461 / 463

页数：3