Elastic Properties of the Annular Ligament of the Human Stapes-AFM Measurement

被引:16
作者
Kwacz, Monika [1 ]
Rymuza, Zygmunt [1 ]
Michalowski, Marcin [1 ]
Wysocki, Jaroslaw [2 ]
机构
[1] Warsaw Univ Technol, Fac Mechatron, Inst Micromech & Photon, PL-02525 Warsaw, Poland
[2] Med Univ Warsaw, Dept Otolaryngol, Warsaw, Poland
来源
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY | 2015年 / 16卷 / 04期
关键词
annular ligament; stapes; elastic modulus; atomic force microscopy; ATOMIC-FORCE MICROSCOPY; FINITE-ELEMENT-ANALYSIS; HUMAN MIDDLE-EAR; RAT STAPEDIOVESTIBULAR JOINT; LOCAL MECHANICAL-PROPERTIES; HUMAN TEMPORAL BONES; OUTER HAIR-CELLS; SOUND-TRANSMISSION; OSSICULAR CHAIN; INPUT IMPEDANCE;
D O I
10.1007/s10162-015-0525-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Elastic properties of the human stapes annular ligament were determined in the physiological range of the ligament deflection using atomic force microscopy and temporal bone specimens. The annular ligament stiffness was determined based on the experimental load-deflection curves. The elastic modulus (Young's modulus) for a simplified geometry was calculated using the Kirchhoff-Love theory for thin plates. The results obtained in this study showed that the annular ligament is a linear elastic material up to deflections of about 100 nm, with a stiffness of about 120 N/m and a calculated elastic modulus of about 1.1 MPa. These parameters can be used in numerical and physical models of the middle and/or inner ear.
引用
收藏
页码:433 / 446
页数:14
相关论文
共 61 条
[1]  
Asai M, 1999, ACTA OTO-LARYNGOL, V119, P356
[2]   ATOMIC FORCE MICROSCOPE [J].
BINNIG, G ;
QUATE, CF ;
GERBER, C .
PHYSICAL REVIEW LETTERS, 1986, 56 (09) :930-933
[3]   MORPHOLOGY OF STAPEDIOVESTIBULAR JOINT [J].
BOLZ, EA ;
LIM, DJ .
ACTA OTO-LARYNGOLOGICA, 1972, 73 (01) :10-&
[4]  
BRUNNER H, 1954, AMA ARCH OTOLARYNGOL, V59, P18
[5]  
Cancura W, 1979, ARCH OTORHINOLARYNGO, V107, P27
[6]   Measurements of stapes velocity in live human ears [J].
Chien, Wade ;
Rosowski, John J. ;
Ravicz, Michael E. ;
Rauch, Steven D. ;
Smullen, Jennifer ;
Merchant, Saumil N. .
HEARING RESEARCH, 2009, 249 (1-2) :54-61
[7]   Accurate force measurement in the atomic force microscope: a microfabricated array of reference springs for easy cantilever calibration [J].
Cumpson, PJ ;
Hedley, J ;
Zhdan, P .
NANOTECHNOLOGY, 2003, 14 (08) :918-924
[8]   Fixation and detachment of superior and anterior malleolar ligaments in human middle ear: Experiment and modeling [J].
Dai, Chenkal ;
Cheng, Tao ;
Wood, Mark W. ;
Gan, Rong Z. .
HEARING RESEARCH, 2007, 230 (1-2) :24-33
[9]   Viscoelastic properties of zonal articular chondrocytes measured by atomic force microscopy [J].
Darling, E. M. ;
Zauscher, S. ;
Guilak, F. .
OSTEOARTHRITIS AND CARTILAGE, 2006, 14 (06) :571-579
[10]   A method for interpreting the data from depth-sensing indentation instruments [J].
Doerner, M. F. ;
Nix, W. D. .
JOURNAL OF MATERIALS RESEARCH, 1986, 1 (04) :601-609