Allosteric Modulators of Metabotropic Glutamate Receptor 5 for Treatment of Schizophrenia

被引：0
|
作者：
Conn, P. J. [1 ,2 ]
Stauffer, S. R. [1 ,2 ,3 ]
Zhou, S. [1 ,2 ]
Manka, J. [1 ,2 ]
Williams, R. [1 ,2 ]
Noetzel, M. J. [2 ]
Gregory, K. J. [2 ]
Vinson, P. [1 ,2 ]
Niswender, C. M. [1 ,2 ]
Jones, C. K. [1 ,2 ]
Steckler, T. [4 ]
MacDonald, G. [4 ]
Lindsley, C. W. [1 ,2 ,3 ]
机构：
[1] Vanderbilt Ctr Neurosci Drug Discovery, Nashville, TN USA
[2] Vanderbilt Univ, Med Ctr, Dept Pharmacol, Nashville, TN 37212 USA
[3] Vanderbilt Univ, Dept Chem, Nashville, TN 37212 USA
[4] Janssen PRD, Neurosci Drug Discovery, Beerse, Belgium
来源：
CURRENT NEUROPHARMACOLOGY | 2011年 / 9卷
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
31
引用
收藏
页码：11 / 12
页数：2
相关论文
共 50 条
  • [1] Positive allosteric modulators of the metabotropic glutamate receptor 2 for the treatment of schizophrenia
    Fraley, Mark E.
    EXPERT OPINION ON THERAPEUTIC PATENTS, 2009, 19 (09) : 1259 - 1275
  • [2] Metabotropic glutamate receptor 5-positive allosteric modulators for the treatment of schizophrenia (2004-2012)
    Lindsley, Craig W.
    Stauffer, Shaun R.
    PHARMACEUTICAL PATENT ANALYST, 2013, 2 (01) : 93 - 108
  • [3] Novel allosteric modulators of metabotropic glutamate receptors subtypes 2 and 5 for the treatment of schizophrenia
    Jones, C. K.
    Xiang, Z.
    Jones, P. J.
    Byun, N. E.
    Hackler, E. A.
    Rodriguez, A. L.
    Ayala, J. E.
    Niswender, C. M.
    Jadhav, S.
    Sheffler, D. J.
    Hammond, A. S.
    Barret, R.
    Thompson, A. D.
    Williams, R.
    Gore, J. C.
    Weaver, C. D.
    Lindsley, C. W.
    Conn, P. J.
    NEUROPHARMACOLOGY, 2008, 55 (04) : 603 - 603
  • [4] Positive allosteric modulators of metabotropic glutamate 2 receptors in schizophrenia treatment
    Ellaithy, Amr
    Younkin, Jason
    Gonzalez-Maeso, Javier
    Logothetis, Diomedes E.
    TRENDS IN NEUROSCIENCES, 2015, 38 (08) : 506 - 516
  • [5] The Role of Metabotropic Glutamate Receptor Allosteric Modulators in the Investigation and Treatment of Gliomas
    Nickols, Hilary
    Conn, P.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2011, 70 (06): : 510 - 510
  • [6] Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype
    Rosse, Gerard
    ACS MEDICINAL CHEMISTRY LETTERS, 2013, 4 (06): : 500 - 501
  • [7] A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5
    O'Brien, JA
    Lemaire, W
    Chen, TB
    Chang, RSL
    Jacobson, MA
    Ha, SN
    Lindsley, CW
    Schaffhauser, HJ
    Sur, C
    Pettibone, DJ
    Conn, PJ
    Williams, DL
    MOLECULAR PHARMACOLOGY, 2003, 64 (03) : 731 - 740
  • [8] Positive allosteric modulators of metabotropic glutamate receptor 5: A new generation of antipsychotics?
    Mutel, V
    Bessis, AS
    Epping-Jordan, M
    Le Poul, E
    Ludwig, B
    Poli, SM
    Rocher, JP
    NEUROPSYCHOPHARMACOLOGY, 2005, 30 : S30 - S30
  • [9] Metabotropic glutamate receptor 5 in the pathology and treatment of schizophrenia
    Matosin, Natalie
    Newell, Kelly A.
    NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2013, 37 (03): : 256 - 268
  • [10] Group II metabotropic glutamate receptor agonists and positive allosteric modulators as novel treatments for schizophrenia
    Fell, Matthew J.
    McKinzie, David L.
    Monn, James A.
    Svensson, Kjell A.
    NEUROPHARMACOLOGY, 2012, 62 (03) : 1473 - 1483
12345