Foxn4 -: a new member of the forkhead gene family is expressed in the retina

被引：36
作者：
Gouge, A
Holt, J
Hardy, AP
Sowden, JC
Smith, HK
机构：
[1] UCL, Wolfson Inst Biomed Res, Dept Biol, London WC1E 6BT, England
[2] UCL, Galton Lab, Dept Biol, London NW1 2HE, England
[3] UCL, Inst Child Hlth, London WC1N 1EH, England
来源：
MECHANISMS OF DEVELOPMENT | 2001年 / 107卷 / 1-2期
关键词：
mouse; forkhead; Foxn4; retina; spinal cord; hindbrain; in situ hybridisation; proliferation; ocular retardation;
D O I：
10.1016/S0925-4773(01)00465-8
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We report the cloning and expression of a novel murine forkhead/winged helix family member - Foxn4 that is expressed during neural development in the retina, the ventral hindbrain and spinal cord and dorsal midbrain. Retinal Foxn4 expression is associated with the zone of proliferating progenitor cells. In the Mouse mutant ocular retardation (or(J)), Foxn4 expression in the retina is significantly reduced and terminates prematurely. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
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收藏
页码：203 / 206
页数：4
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