Quantitative Assessment of Gait Bradykinesia in Parkinson's Disease Using a Portable Gait Rhythmogram

被引：0

作者：

Utsumi, Hiroya ^{[1
]}

Terashi, Hiroo ^{[1
]}

Ishimura, Yohei ^{[1
]}

Takazawa, Tomoko ^{[1
]}

Hayashi, Akito ^{[3
]}

Mochizuki, Hideki ^{[4
]}

Okuma, Yasuyuki ^{[5
]}

Orimo, Satoshi ^{[6
]}

Takahashi, Kazushi ^{[7
]}

Yoneyama, Mitsuru ^{[8
]}

Mitoma, Hiroshi ^{[2
]}

机构：

[1] Tokyo Med Univ, Dept Neurol, Shinjuku Ku, Tokyo 1600023, Japan

[2] Tokyo Med Univ, Dept Med Educ, Shinjuku Ku, Tokyo 1600023, Japan

[3] Juntendo Univ, Urayasu Hosp, Dept Rehabil, Chiba 2790021, Japan

[4] Kitasato Univ, Dept Neurol, Sagamihara, Kanagawa 2520374, Japan

[5] Juntendo Univ, Shizuoka Hosp, Dept Neurol, Shizuoka 4102295, Japan

[6] Kanto Chuo Hosp, Dept Neurol, Setagaya Ku, Tokyo 1588531, Japan

[7] Keio Univ, Dept Neurol, Shinjuku Ku, Tokyo 1608582, Japan

[8] Mitsubishi Chem Grp Sci & Technol Res Ctr Inc, Yokohama, Kanagawa 2270033, Japan

来源：

ACTA MEDICA OKAYAMA | 2012年 / 66卷 / 01期

关键词：

Parkinson's disease; gait disorders; portable gait rhythmogram;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

To quantify gait bradykinesia during daily activity in patients with Parkinson's disease (PD), we measured movement-induced accelerations over more than 24h in 50 patients with PD and 17 age-matched normal controls, using a new device, the portable gait rhythmogram. Acceleration values induced by various movements, averaged each 10 min, exhibited a gamma distribution. The mean value of the distribution curve was used as an index of the "amount of overall movement per 24 h". Characteristic changes were observed in both the gait cycle and gait acceleration. Daring hypokinesia, the gait cycle became either faster or slower. A number of patients with marked akinesia/bradykinesia showed a reduced and narrow range of gait acceleration, i.e., a range of floor reaction forces. The results suggest that assessment of the combination of changes in gait cycle and gait acceleration can quantitatively define the severity of gait bradykinesia.

引用

页码：31 / 40

页数：10

共 18 条

[1]

[Anonymous], 1982, Mov. Disorders

[2]

[Anonymous], 1987, RECENT DEV PARKINSON

[3] HUMAN NEURONAL CONTROL OF AUTOMATIC FUNCTIONAL MOVEMENTS - INTERACTION BETWEEN CENTRAL PROGRAMS AND AFFERENT INPUT [J].

DIETZ, V .

PHYSIOLOGICAL REVIEWS, 1992, 72 (01) :33-69

[4] REACTION-TIME IN PARKINSONS-DISEASE [J].

EVARTS, EV ;

TERAVAINEN, H ;

CALNE, DB .

BRAIN, 1981, 104 (MAR) :167-186

[5] VISUAL CLOSED-LOOP AND OPEN-LOOP CHARACTERISTICS OF VOLUNTARY MOVEMENT IN PATIENTS WITH PARKINSONISM AND INTENTION TREMOR [J].

FLOWERS, KA .

BRAIN, 1976, 99 (JUN) :269-310

[6] A PHYSIOLOGICAL MECHANISM OF BRADYKINESIA [J].

HALLETT, M ;

KHOSHBIN, S .

BRAIN, 1980, 103 (JUN) :301-314

[7]

JANKOVIC J, 1987, HDB PARKINSONS DIS, P99

[8] THE MYSTERIOUS MOTOR FUNCTION OF THE BASAL GANGLIA - THE ROBERT WARTENBERG LECTURE [J].

MARSDEN, CD .

NEUROLOGY, 1982, 32 (05) :514-539

[9] Characteristics of parkinsonian and ataxic gaits: a study using surface electromyograms, angular displacements and floor reaction forces [J].

Mitoma, H ;

Hayashi, R ;

Yanagisawa, N ;

Tsukagoshi, H .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 2000, 174 (01) :22-39

[10] 24-Hour Recording of Parkinsonian Gait Using a Portable Gait Rhythmogram [J].

Mitoma, Hiroshi ;

Yoneyama, Mitsuru ;

Orimo, Satoshi .

INTERNAL MEDICINE, 2010, 49 (22) :2401-2408

← 1 2 →