Two-Photon Lysotrackers for in Vivo Imaging

被引：44
|
作者：
Son, Ji Hoon [1 ]
Lim, Chang Su [1 ]
Han, Ji Hee [1 ]
Danish, Isravel Antony [1 ]
Kim, Hwan Myung [2 ]
Cho, Bong Rae [1 ]
机构：
[1] Korea Univ, Dept Chem, Seoul 136701, South Korea
[2] Ajou Univ, Div Energy Syst Res, Suwon 443749, South Korea
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 19期
基金：
新加坡国家研究基金会;
关键词：
FLUORESCENT-PROBES; ACIDIC VESICLES; DERIVATIVES; IONS;
D O I：
10.1021/jo201504h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report two-photon Lysotrackers (CLT-blue and CLT-yellow) that can be excited by 750-840 nm femto-second laser pulses and emit at 470 and 550 nm, respectively. They can be easily loaded into cells and tissue slices for visualization of lysosomes in live cells and tissues for a long period of time through two-photon microscopy. When combined with appropriate two-photon probes for other biological targets, these novel probes would greatly facilitate the two-photon microscopy colocalization experiments.
引用
收藏
页码：8113 / 8116
页数：4
相关论文
共 50 条
  • [41] Carborane enhanced two-photon absorption of tribranched fluorophores for fluorescence microscopy imaging
    Zhu, Lin
    Lv, Wen
    Liu, Shujuan
    Yan, Hong
    Zhao, Qiang
    Huang, Wei
    CHEMICAL COMMUNICATIONS, 2013, 49 (90) : 10638 - 10640
  • [42] A fluorescent probe for bisulfite ions: its application to two-photon tissue imaging
    Agarwalla, Hridesh
    Pal, Suman
    Paul, Anirban
    Jun, Yong Woong
    Bae, Juryang
    Ahn, Kyo Han
    Srivastava, Divesh N.
    Das, Amitava
    JOURNAL OF MATERIALS CHEMISTRY B, 2016, 4 (48) : 7888 - 7894
  • [43] Two-photon probes based on arylsulfonyl azides: Fluorescence detection and imaging of biothiols
    Singha, Subhankar
    Kim, Dokyoung
    Rao, Alla Sreenivasa
    Wang, Taejun
    Kim, Ki Hean
    Lee, Kyung-Ha
    Kim, Kyong-Tai
    Ahn, Kyo Han
    DYES AND PIGMENTS, 2013, 99 (02) : 308 - 315
  • [44] Development of a Two-Photon Fluorescent Probe for Imaging of Endogenous Formaldehyde in Living Tissues
    Tang, Yonghe
    Kong, Xiuqi
    Xu, An
    Dong, Baoli
    Lin, Weiying
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (10) : 3356 - 3359
  • [45] Two-photon and three-photon absorption in dinaphthoporphycenes
    Rao, S. Venugopal
    Prashant, T. Shuvan
    Swain, Debasis
    Sarma, Tridib
    Panda, Pradeepta K.
    Tewari, Surya P.
    CHEMICAL PHYSICS LETTERS, 2011, 514 (1-3) : 98 - 103
  • [46] Dicyanostilbene-derived two-photon fluorescence dyes with large two-photon absorption cross sections
    Huang, Chibao
    Lin, Changhua
    Ren, Anxiang
    Yang, Nianfa
    JOURNAL OF MOLECULAR STRUCTURE, 2011, 1006 (1-3) : 91 - 95
  • [47] One-Photon and Two-Photon Mitochondrial Fluorescent Probes Based on a Rhodol Chromophore
    Poronik, Yevgen M.
    Bernas, Tytus
    Wrzosek, Antoni
    Banasiewicz, Marzena
    Szewczyk, Adam
    Gryko, Daniel T.
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 7 (02) : 411 - 415
  • [48] Target-Activated Modulation of Dual-Color and Two-Photon Fluorescence of Graphene Quantum Dots for in Vivo Imaging of Hydrogen Peroxide
    Zhao, Wenjie
    Li, Yinhui
    Yang, Sheng
    Chen, Yun
    Zheng, Jing
    Liu, Changhui
    Qing, Zhihe
    Li, Jishan
    Yang, Ronghua
    ANALYTICAL CHEMISTRY, 2016, 88 (09) : 4833 - 4840
  • [49] Design of a two-photon fluorescent probe for selective recognition of Au(III) over Au(I) and its application of imaging in vitro and in vivo
    Wang, Wenjuan
    Huang, Yinliang
    Wang, Shumin
    Zhou, Yujie
    Huang, Wei
    Feng, Yan
    Zhang, Wan
    Yu, Wenxin
    Zhou, Qiang
    Chen, Man
    Fang, Min
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2017, 187 : 110 - 118
  • [50] Two-Photon Fluorescent Probes for Bioimaging
    Yao, Sheng
    Belfield, Kevin D.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2012, 2012 (17) : 3199 - 3217
12345