Two-Photon Lysotrackers for in Vivo Imaging

被引：44
|
作者：
Son, Ji Hoon [1 ]
Lim, Chang Su [1 ]
Han, Ji Hee [1 ]
Danish, Isravel Antony [1 ]
Kim, Hwan Myung [2 ]
Cho, Bong Rae [1 ]
机构：
[1] Korea Univ, Dept Chem, Seoul 136701, South Korea
[2] Ajou Univ, Div Energy Syst Res, Suwon 443749, South Korea
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 19期
基金：
新加坡国家研究基金会;
关键词：
FLUORESCENT-PROBES; ACIDIC VESICLES; DERIVATIVES; IONS;
D O I：
10.1021/jo201504h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report two-photon Lysotrackers (CLT-blue and CLT-yellow) that can be excited by 750-840 nm femto-second laser pulses and emit at 470 and 550 nm, respectively. They can be easily loaded into cells and tissue slices for visualization of lysosomes in live cells and tissues for a long period of time through two-photon microscopy. When combined with appropriate two-photon probes for other biological targets, these novel probes would greatly facilitate the two-photon microscopy colocalization experiments.
引用
收藏
页码：8113 / 8116
页数：4
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