New model tackles sticky problem of getting drugs past mucus

被引：2
作者：
Bhatia, Juhie
机构：
来源：
NATURE MEDICINE | 2015年 / 21卷 / 04期
关键词：
POLYMERIC NANOPARTICLES; DELIVERY;
D O I：
10.1038/nm0415-301
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：301 / 301
页数：1
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共 4 条
[1]   Mucus as a Barrier to Drug Delivery - Understanding and Mimicking the Barrier Properties [J].
Boegh, Marie ;
Nielsen, Hanne Morck .
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2015, 116 (03) :179-186
[2]   Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption [J].
Boegh, Marie ;
Baldursdottir, Stefania G. ;
Mullertz, Anette ;
Nielsen, Hanne M. .
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2014, 87 (02) :227-235
[3]   Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers [J].
Ensign, Laura M. ;
Cone, Richard ;
Hanes, Justin .
ADVANCED DRUG DELIVERY REVIEWS, 2012, 64 (06) :557-570
[4]   Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus [J].
Lai, Samuel K. ;
O'Hanlon, D. Elizabeth ;
Harrold, Suzanne ;
Man, Stan T. ;
Wang, Ying-Ying ;
Cone, Richard ;
Hanes, Justin .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (05) :1482-1487
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