Tackling transcription factors: challenges in antitumor therapy

被引：20

作者：

Grivas, Petros D. ^{[2
]}

Kiaris, Hippokratis ^{[1
]}

Papavassiliou, Athanasios G. ^{[1
]}

机构：

[1] Univ Athens, Sch Med, Dept Biol Chem, GR-11527 Athens, Greece

[2] Univ Michigan, Div Hematol Oncol, Dept Internal Med, Ann Arbor, MI 48109 USA

来源：

TRENDS IN MOLECULAR MEDICINE | 2011年 / 17卷 / 10期

关键词：

CANCER; INHIBITION;

D O I：

10.1016/j.molmed.2011.06.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：537 / 538

页数：2

共 10 条

[1] Inhibition of transcription factors with small organic molecules [J].

Berg, Thorsten .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2008, 12 (04) :464-471

[2] Translating DNA damage into cancer cell death-A roadmap for E2F1 apoptotic signalling and opportunities for new drug combinations to overcome chemoresistance [J].

Engelmann, David ;

Puetzer, Brigitte M. .

DRUG RESISTANCE UPDATES, 2010, 13 (4-5) :119-131

[3] The transcription factor ATF5: role in neurodevelopment and neural tumors [J].

Greene, Lloyd A. ;

Lee, Hae Young ;

Angelastro, James M. .

JOURNAL OF NEUROCHEMISTRY, 2009, 108 (01) :11-22

[4] Targeting MET as a strategy to overcome crosstalk-related resistance to EGFR inhibitors [J].

Karamouzis, Michalis V. ;

Konstantinopoulos, Panagiotis A. ;

Papavassiliou, Athanasios G. .

LANCET ONCOLOGY, 2009, 10 (07) :709-717

[5] Targeting transcription factors for cancer gene therapy [J].

Libermann, TA ;

Zerbini, LF .

CURRENT GENE THERAPY, 2006, 6 (01) :17-33

[6] Direct inhibition of the NOTCH transcription factor complex [J].

Moellering, Raymond E. ;

Cornejo, Melanie ;

Davis, Tina N. ;

Del Bianco, Cristina ;

Aster, Jon C. ;

Blacklow, Stephen C. ;

Kung, Andrew L. ;

Gilliland, D. Gary ;

Verdine, Gregory L. ;

Bradner, James E. .

NATURE, 2009, 462 (7270) :182-U57

[7] Targeting HOX and PBX transcription factors in ovarian cancer [J].

Morgan, Richard ;

Plowright, Lynn ;

Harrington, Kevin J. ;

Michael, Agnieszka ;

Pandha, Hardev S. .

BMC CANCER, 2010, 10

[8] Defining and targeting transcription factors in cancer [J].

Aisling M Redmond ;

Jason S Carroll .

Genome Biology, 10 (7)

[9] Small-molecule regulators that mimic transcription factors [J].

Rodriguez-Martinez, Jose A. ;

Peterson-Kaufman, Kimberly J. ;

Ansari, Aseem Z. .

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2010, 1799 (10-12) :768-774

[10]

Yue P, 2009, EXPERT OPIN INV DRUG, V18, P45, DOI [10.1517/13543780802565791, 10.1517/13543780802565791 ]

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