Eco-friendly synthesis of silver nanoparticles using leaf extract of Flemingia wightiana: spectral characterization, antioxidant and anticancer activity studies

被引：19

作者：

Reddy, Netala Vasudeva ^{[1
]}

Satyanarayana, Bethu Murali ^{[2
]}

Sivasankar, Sana ^{[3
]}

Pragathi, Duggina ^{[1
]}

Subbaiah, Kotakadi Venkata ^{[4
]}

Vijaya, Tartte ^{[5
]}

机构：

[1] Sri Venkateswara Univ, Dept Biotechnol, Tirupati, Andhra Pradesh, India

[2] CSIR IICT, Biol & Toxicol Div, Hyderabad, Telangana, India

[3] Yogivemana Univ, Dept Chem, Kadapa, Andhra Pradesh, India

[4] Sri Venkateswara Univ, DST PURSE Ctr, Tirupati, Andhra Pradesh, India

[5] Sri Venkateswara Univ, Dept Bot, Tirupati, Andhra Pradesh, India

来源：

SN APPLIED SCIENCES | 2020年 / 2卷 / 05期

关键词：

Flemingia wightiana; Silver nanoparticles; Antioxidant activity; Cytotoxicity; SKOV3; COLO205; ANTIBACTERIAL ACTIVITY; DYE DEGRADATION; TOXICITY; GROWTH;

D O I：

10.1007/s42452-020-2702-7

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In the present investigation, we report simple, robust and eco-friendly synthesis of silver nanoparticles (AgNPs) using leaf extract of Flemingia wightiana. The leaf extract of F. wightiana acts as reducing agent which reduces the silver ions into FW-AgNPs, as well as stabilizing agent by capping around them. Biosynthesized FW-AgNPs were characterized by different spectroscopic techniques. UV-Vis spectrum showed the characteristic SPR peak between 380 and 460 nm. EDX analysis revealed the presence of metallic silver at 3 keV. XRD analysis clearly revealed that FW-AgNPs are crystalline in nature with FCC structure. TEM analysis depicted the spherical morphology with 20-40 nm in size. DLS analysis showed that average hydrodynamic size and PDI value of FW-AgNPs were found to be 47.6 nm and 4.5 respectively. Biosynthesized FW-AgNPs showed high negative zeta potential value of -25.3 mV. FTIR analysis revealed the participation of polyphenols and proteins in the bioreduction and stabilization of FW-AgNPs. FW-AgNPs showed strong DPPH and H2O2 scavenging activity with IC50 values of 71.96 and 80.59 mu g/mL respectively. Further FW-AgNPs also showed effective cytotoxicity against cancer cells including SKOV3 and COLO205 with maximum inhibition of 83.2% and 75.9% respectively.

引用

页数：10

共 69 条

[1] Antioxidant and antibacterial activity of silver nanoparticles biosynthesized using Chenopodium murale leaf extract [J].

Abdel-Aziz, Mohamed S. ;

Shaheen, Mohamed S. ;

El-Nekeety, Aziza A. ;

Abdel-Wahhab, Mosaad A. .

JOURNAL OF SAUDI CHEMICAL SOCIETY, 2014, 18 (04) :356-363

[2] Biosynthesis of silver, gold and silver–gold alloy nanoparticles using Persea americana fruit peel aqueous extract for their biomedical properties [J].

Adebayo A.E. ;

Oke A.M. ;

Lateef A. ;

Oyatokun A.A. ;

Abisoye O.D. ;

Adiji I.P. ;

Fagbenro D.O. ;

Amusan T.V. ;

Badmus J.A. ;

Asafa T.B. ;

Beukes L.S. ;

Gueguim-Kana E.B. ;

Abbas S.H. .

Nanotechnology for Environmental Engineering, 2019, 4 (1)

[3] Antileishmanial effect of silver nanoparticles and their enhanced antiparasitic activity under ultraviolet light [J].

Allahverdiyev, Adil M. ;

Abamor, Emrah Sefik ;

Bagirova, Malahat ;

Ustundag, Cem B. ;

Kaya, Cengiz ;

Kaya, Figen ;

Rafailovich, Miriam .

INTERNATIONAL JOURNAL OF NANOMEDICINE, 2011, 6 :2705-2714

[4] Biogenic synthesis of silver nanoparticles by leaf extract of Cassia angustifolia [J].

Amaladhas, T Peter ;

Sivagami, S. ;

Devi, T Akkini ;

Ananthi, N. ;

Velammal, S Priya .

Advances in Natural Sciences: Nanoscience and Nanotechnology, 2012, 3 (04)

[5] Biogenic synthesis of silver nanoparticles using Priva cordifolia leaf extract (PC@AgNPs) a potent antioxidant, antibacterial and catalytic activity [J].

Ananda, A. P. ;

Krishnamurthy, N. B. ;

Savitha, K. R. ;

Nagendra, B. S. .

SN APPLIED SCIENCES, 2019, 1 (07)

[6]

[Anonymous], IND ANAL REPORT REGI

[7]

[Anonymous], INT J PHARM PHARM SC

[8]

[Anonymous], LEGUMES INDIA DEHRA

[9] Characterization of silver nanoparticles biosynthesized using Amaranthus cruentus [J].

Baghani, Mohsen ;

Es-haghi, Ali .

BIOINSPIRED BIOMIMETIC AND NANOBIOMATERIALS, 2020, 9 (03) :129-136

[10] Potential anticancer activity of biogenic silver nanoparticles using leaf extract of Rhynchosia suaveolens: an insight into the mechanism [J].

Bethu, Murali Satyanarayana ;

Netala, Vasudeva Reddy ;

Domdi, Latha ;

Tartte, Vijaya ;

Janapala, Venkateswara Rao .

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, 2018, 46 :S104-S114

← 1 2 3 4 5 6 7 →